AIM: To evaluate the effect of testosterone (T) on adiponectin serum levels in transsexual female patients. METHODS: We measured adiponectin, leptin, luteinizing hormone and follicle stimulating hormone, T, estradiol, lipid profile, biochemical parameters and body composition in 16 transsexual female patients at baseline and after 6 months of T treatment (100 mg Testoviron Depot /10 days, i.m.). RESULTS: Adiponectin levels were 16.9 +/- 7.3 mg/mL at baseline and 13.5 +/- 7.4 mg/mL at month 6 of T treatment (P < 0.05). Leptin and high-density lipoprotein cholesterol decreased significantly, whereas body mass index, waist circumference and lean body mass increased significantly after 6 months of T treatment. No changes in insulin or Homeostasis Model Assessment were detected. CONCLUSION: T can significantly reduce adiponectin serum levels in transsexual female patients.
AIM: To evaluate the effect of testosterone (T) on adiponectin serum levels in transsexual female patients. METHODS: We measured adiponectin, leptin, luteinizing hormone and follicle stimulating hormone, T, estradiol, lipid profile, biochemical parameters and body composition in 16 transsexual female patients at baseline and after 6 months of T treatment (100 mg Testoviron Depot /10 days, i.m.). RESULTS:Adiponectin levels were 16.9 +/- 7.3 mg/mL at baseline and 13.5 +/- 7.4 mg/mL at month 6 of T treatment (P < 0.05). Leptin and high-density lipoprotein cholesterol decreased significantly, whereas body mass index, waist circumference and lean body mass increased significantly after 6 months of T treatment. No changes in insulin or Homeostasis Model Assessment were detected. CONCLUSION: T can significantly reduce adiponectin serum levels in transsexual female patients.
Authors: A D Fisher; G Senofonte; C Cocchetti; G Guercio; V Lingiardi; M C Meriggiola; M Mosconi; G Motta; J Ristori; A M Speranza; M Pierdominici; M Maggi; G Corona; F Lombardo Journal: J Endocrinol Invest Date: 2021-10-22 Impact factor: 4.256
Authors: Hua Ling; Dawn M Waterworth; Heide A Stirnadel; Toni I Pollin; Philip J Barter; Y Antero Kesäniemi; Robert W Mahley; Ruth McPherson; Gérard Waeber; Thomas P Bersot; Jonathan C Cohen; Scott M Grundy; Vincent E Mooser; Braxton D Mitchell Journal: Obesity (Silver Spring) Date: 2009-01-22 Impact factor: 5.002
Authors: Joshua F Yarrow; Luke A Beggs; Christine F Conover; Sean C McCoy; Darren T Beck; Stephen E Borst Journal: PLoS One Date: 2012-10-10 Impact factor: 3.240