| Literature DB >> 16855365 |
Abstract
Factor FXIII (FXIII) is a plasma transglutaminase that catalyzes the cross link formation between fibrin chains to stabilize the clot. Beside it s function in hemostasis FXIII has a role in wound healing and embryo implantation--processes that involve angiogenesis. In this review we discuss the role of FXIII in angiogenesis and the molecular mechanisms underlying its pro-angiogenic effect. In addition, FXIII role in wound repair is discussed.Mesh:
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Year: 2006 PMID: 16855365 DOI: 10.1159/000093562
Source DB: PubMed Journal: Pathophysiol Haemost Thromb ISSN: 1424-8832