Literature DB >> 16855173

Leptin is a link between adipose tissue and inflammation.

Peter Härle1, Rainer H Straub.   

Abstract

Leptin is a hormone of the pluripotent white adipose tissue and confers a multitude of regulatory functions within the organism. It controls the energy storage, lipoprotein metabolism, acute phase reactants, sex hormones and glucocorticoid metabolism, and immune function. In this review, we describe these multiple functions of leptin, the regulation of leptin expression, and how leptin can modulate the immune system via direct and indirect mechanisms. We show how leptin can be a link between the adipose tissue and inflammation.

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Year:  2006        PMID： 16855173     DOI： 10.1196/annals.1351.044

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  15 in total

Review 1.  Leptin as a metabolic link to multiple sclerosis.

Authors:  Giuseppe Matarese; Pietro Biagio Carrieri; Silvana Montella; Veronica De Rosa; Antonio La Cava
Journal:  Nat Rev Neurol       Date:  2010-07-06       Impact factor: 42.937

2.  Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease.

Authors:  Mobin Malik; Tisha M Suboc; Sudhi Tyagi; Nita Salzman; Jingli Wang; Rong Ying; Michael J Tanner; Mamatha Kakarla; John E Baker; Michael E Widlansky
Journal:  Circ Res       Date:  2018-10-12       Impact factor: 17.367

3.  Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.

Authors:  Giuseppe Matarese; Claudio Procaccini; Ciro Menale; Jae Geun Kim; Jung Dae Kim; Sabrina Diano; Nadia Diano; Veronica De Rosa; Marcelo O Dietrich; Tamas L Horvath
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-25       Impact factor: 11.205

4.  Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents.

Authors:  Grewo Lim; Shuxing Wang; Yi Zhang; Yinghong Tian; Jianren Mao
Journal:  J Clin Invest       Date:  2009-01-12       Impact factor: 14.808

Review 5.  Leptin signaling in brain: A link between nutrition and cognition?

Authors:  Christopher D Morrison
Journal:  Biochim Biophys Acta       Date:  2008-12-24

6.  Risk of colonic cancer is not higher in the obese Lep(ob) mouse model compared to lean littermates.

Authors:  Angelos K Sikalidis; Mark D Fitch; Sharon E Fleming
Journal:  Pathol Oncol Res       Date:  2013-06-29       Impact factor: 3.201

7.  Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant.

Authors:  Salma M A Musaad; Tia Patterson; Mark Ericksen; Mark Lindsey; Kim Dietrich; Paul Succop; Gurjit K Khurana Hershey
Journal:  J Allergy Clin Immunol       Date:  2009-05-12       Impact factor: 10.793

Review 8.  Regulatory T cells, mTOR kinase, and metabolic activity.

Authors:  Claudio Procaccini; Giuseppe Matarese
Journal:  Cell Mol Life Sci       Date:  2012-07-04       Impact factor: 9.261

9.  The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study.

Authors:  Oliver P Stannus; Graeme Jones; Stephen J Quinn; Flavia M Cicuttini; Dawn Dore; Changhai Ding
Journal:  Arthritis Res Ther       Date:  2010-05-19       Impact factor: 5.156

10.  Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1.

Authors:  Zhen Guo; Yixuan Zhang; Chang Liu; Ji Youn Youn; Hua Cai
Journal:  Diabetes       Date:  2021-06-14       Impact factor: 9.337
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