Literature DB >> 16854995

Estimation of the sexual transmission of HIV in Kenya and Uganda on the trans-Africa highway: the continuing role for prevention in high risk groups.

C N Morris1, A G Ferguson.   

Abstract

OBJECTIVE: To explore the effect of transactional sex on the trans-Africa highway from Mombasa-Kampala in contributing to the HIV epidemic and the impact that an effective prevention intervention could have.
METHODS: Variables for input into a simple model of HIV prevention, AVERT, were derived from a study of hot spots of transactional sex on the trans-Africa highway. Diaries were completed by a sample of sex workers at selected sites of transactional sex for a period of 28 consecutive days. Key information elicited included numbers, types and occupations of clients, numbers of liaisons, sexual acts in each liaison, and condom use. 857 diaries were distributed and 578 received and usable in 30 sites. A sexual patterning matrix was completed by 202 truckers at the Malaba border point as part of a health seeking behaviour survey. Two methods were employed to estimate female sex worker (FSW) numbers on the highway. FSW focus group discussions (FGDs) at 15 sites were carried out and included questioning on the number of sex workers at the site. As most transactional sex on the highway is centred on bars and lodgings, a patron census and survey of 1007 bars and lodgings was carried out which included questions on the presence and proportions of FSWs among the clientele.
RESULTS: There are an estimated 8000 FSWs on the trans-Africa highway from Mombasa to Kampala. Annual numbers of different sexual partners per FSW were 129, annual numbers of sexual acts per FSW were 634, percentage of sexual acts protected by condom use was 77.7%. Using these input data an estimated 3200-4148 new HIV infections occur on this portion of the trans-Africa highway in 1 year. Having a 90% condom use programme in place could prevent almost two thirds of these infections and cumulative incidence would decline from 1.29% to 0.42%.
CONCLUSIONS: In generalised epidemics there has been a debate as to the place of targeted interventions. In the current east African epidemic we show that a targeted intervention could have significant impact in averting HIV infections related to the trans-Africa highway.

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Year:  2006        PMID: 16854995      PMCID: PMC2563851          DOI: 10.1136/sti.2006.020933

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  9 in total

Review 1.  Back to basics in HIV prevention: focus on exposure.

Authors:  Elizabeth Pisani; Geoff P Garnett; Nicholas C Grassly; Tim Brown; John Stover; Catherine Hankins; Neff Walker; Peter D Ghys
Journal:  BMJ       Date:  2003-06-21

2.  Using diaries to measure parameters of transactional sex: an example from the Trans-Africa highway in Kenya.

Authors:  Alan G Ferguson; Chester N Morris; Cecilia W Kariuki
Journal:  Cult Health Sex       Date:  2006 Mar-Apr

3.  AVERT: a user-friendly model to estimate the impact of HIV/sexually transmitted disease prevention interventions on HIV transmission.

Authors:  T M Rehle; T J Saidel; S E Hassig; P D Bouey; E M Gaillard; D C Sokal
Journal:  AIDS       Date:  1998       Impact factor: 4.177

4.  Decreased incidence of sexually transmitted diseases among trucking company workers in Kenya: results of a behavioural risk-reduction programme.

Authors:  D J Jackson; J P Rakwar; B A Richardson; K Mandaliya; B H Chohan; J J Bwayo; J O Ndinya-Achola; H L Martin; S Moses; J K Kreiss
Journal:  AIDS       Date:  1997-06       Impact factor: 4.177

5.  Female-to-male infectivity of HIV-1 among circumcised and uncircumcised Kenyan men.

Authors:  Jared M Baeten; Barbra A Richardson; Ludo Lavreys; Joel P Rakwar; Kishorchandra Mandaliya; Job J Bwayo; Joan K Kreiss
Journal:  J Infect Dis       Date:  2005-01-18       Impact factor: 5.226

6.  Adolescent sexual behavior along the Trans-Africa Highway in Kenya.

Authors:  S Nzyuko; P Lurie; W McFarland; W Leyden; D Nyamwaya; J S Mandel
Journal:  AIDS       Date:  1997-09       Impact factor: 4.177

7.  Epidemiology of HIV infection among long distance truck drivers in Kenya.

Authors:  G G Mbugua; L N Muthami; C W Mutura; S A Oogo; P G Waiyaki; C P Lindan; N Hearst
Journal:  East Afr Med J       Date:  1995-08

8.  Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial.

Authors:  Rupert Kaul; Joshua Kimani; Nico J Nagelkerke; Karoline Fonck; Elizabeth N Ngugi; Florence Keli; Kelly S MacDonald; Ian W Maclean; Job J Bwayo; Marleen Temmerman; Allan R Ronald; Stephen Moses
Journal:  JAMA       Date:  2004-06-02       Impact factor: 56.272

9.  Human immunodeficiency virus infection in long-distance truck drivers in east Africa.

Authors:  J Bwayo; F Plummer; M Omari; A Mutere; S Moses; J Ndinya-Achola; P Velentgas; J Kreiss
Journal:  Arch Intern Med       Date:  1994-06-27
  9 in total
  44 in total

1.  Globalisation, the sex industry, and health.

Authors:  H Ward; S O Aral
Journal:  Sex Transm Infect       Date:  2006-10       Impact factor: 3.519

2.  Sexual and treatment-seeking behaviour for sexually transmitted infection in long-distance transport workers of East Africa.

Authors:  Chester N Morris; Alan G Ferguson
Journal:  Sex Transm Infect       Date:  2007-02-21       Impact factor: 3.519

3.  Inference of global HIV-1 sequence patterns and preliminary feature analysis.

Authors:  Yan Wang; Reda Rawi; Daniel Hoffmann; Binlian Sun; Rongge Yang
Journal:  Virol Sin       Date:  2013-07-27       Impact factor: 4.327

4.  "Over here, it's just drugs, women and all the madness": The HIV risk environment of clients of female sex workers in Tijuana, Mexico.

Authors:  Shira M Goldenberg; Steffanie A Strathdee; Manuel Gallardo; Tim Rhodes; Karla D Wagner; Thomas L Patterson
Journal:  Soc Sci Med       Date:  2011-03-03       Impact factor: 4.634

Review 5.  Mobility and HIV in Central America and Mexico: a critical review.

Authors:  Shira M Goldenberg; Steffanie A Strathdee; Maria D Perez-Rosales; Omar Sued
Journal:  J Immigr Minor Health       Date:  2012-02

6.  Complexities of short-term mobility for sex work and migration among sex workers: violence and sexual risks, barriers to care, and enhanced social and economic opportunities.

Authors:  Shira M Goldenberg; Jill Chettiar; Paul Nguyen; Sabina Dobrer; Julio Montaner; Kate Shannon
Journal:  J Urban Health       Date:  2014-08       Impact factor: 3.671

7.  Correlates of unprotected sex with female sex workers among male clients in Tijuana, Mexico.

Authors:  Shira M Goldenberg; Manuel Gallardo Cruz; Steffanie A Strathdee; Lucie Nguyen; Shirley J Semple; Thomas L Patterson
Journal:  Sex Transm Dis       Date:  2010-05       Impact factor: 2.830

8.  Unmet need for contraception among sex workers in Madagascar.

Authors:  Maria R Khan; Abigail Norris Turner; Audrey Pettifor; Kathleen Van Damme; Ny Lovaniaina Rabenja; Noro Ravelomanana; Teresa Swezey; D'Nyce Williams; Denise Jamieson; Frieda Behets
Journal:  Contraception       Date:  2008-10-28       Impact factor: 3.375

9.  Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa?

Authors:  Andrew Vallely; Ian R Hambleton; Stella Kasindi; Louise Knight; Suzanna C Francis; Tobias Chirwa; Dean Everett; Charles Shagi; Claire Cook; Celia Barberousse; Deborah Watson-Jones; John Changalucha; David Ross; Richard J Hayes
Journal:  PLoS One       Date:  2010-05-14       Impact factor: 3.240

10.  Reproductive health services for populations at high risk of HIV: Performance of a night clinic in Tete province, Mozambique.

Authors:  Yves Lafort; Diederike Geelhoed; Luisa Cumba; Carla das Dores Mosse Lázaro; Wim Delva; Stanley Luchters; Marleen Temmerman
Journal:  BMC Health Serv Res       Date:  2010-05-28       Impact factor: 2.655

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