Literature DB >> 16854761

Secondary cutaneous effects of hydroxyurea: possible pathogenetic mechanisms.

Elisa Zaccaria1, Emanuele Cozzani, Aurora Parodi.   

Abstract

We report the case of a 73-year-old man who had been on hydroxyurea for essential thrombocythemia since 1988. After 12 years of treatment he developed a symmetrical dermatomyositis-like eruption together with a leg ulceration and five squamous cell carcinomas of the face. The possible pathogenetic mechanisms of these known side effects are discussed.

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Year:  2006        PMID： 16854761     DOI： 10.1080/09546630600780494

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN： 0954-6634            Impact factor:   3.359


  4 in total

1.  Malleolar Ulceration Induced by Hydroxyurea Therapy for Chronic Eosinophila.

Authors:  Justin R Bryant; Peter Andrade; Raymond T Hajjar; Christopher R Lumley; Kongkrit Chaiyasate
Journal:  J Am Coll Clin Wound Spec       Date:  2017-01-05

2.  Drug delivery of hydroxyurea to breast cancer using liposomes.

Authors:  Seyed Ebrahim Alavi; Maedeh Koohi Moftakhari Esfahani; Fatemeh Alavi; Fatemeh Movahedi; Azim Akbarzadeh
Journal:  Indian J Clin Biochem       Date:  2012-12-28

3.  In vitro evaluation of the efficacy of liposomal and pegylated liposomal hydroxyurea.

Authors:  Seyed Ebrahim Alavi; Maedeh Koohi Moftakhari Esfahani; Soheil Ghassemi; Azim Akbarzadeh; Gholamhossein Hassanshahi
Journal:  Indian J Clin Biochem       Date:  2013-03-26

Review 4.  Environmental triggers of dermatomyositis: a narrative review.

Authors:  Christina E Bax; Spandana Maddukuri; Adarsh Ravishankar; Lisa Pappas-Taffer; Victoria P Werth
Journal:  Ann Transl Med       Date:  2021-03
  4 in total

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