Literature DB >> 16850960

Peripheral primitive neuroectodermal tumor of the cauda equina in an elderly patient. Case report.

Elizabeth Fabre1, Rémy Guillevin, Fabrice Chretien, Caroline Le Guerinel, Hugues Duffau.   

Abstract

Primitive neuroectodermal tumors (PNETs) are aggressive neoplasms composed predominantly of undifferentiated cells that show evidence of neural differentiation. Although their classification remains disputed, PNETs are recognized as primary tumors in both the central and peripheral nervous systems. These rare tumors usually occur in children or young adults and are typically metastatic to the spinal cord. The authors report the case of a 70-year-old man with no significant medical history, in whom a peripheral PNET was demonstrated that, based on clinical and imaging findings, manifested as a nonspecific intrathecal tumoral process arising from the cauda equina. Although this lesion is rare in the elderly, the authors' case illustrates the importance of making this diagnosis as early as possible so that a treatment plan may be devised. The use of chemotherapy in association with radiotherapy in relation to the resection of the tumor should be reconsidered.

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Year:  2006        PMID: 16850960     DOI: 10.3171/spi.2006.5.1.68

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  7 in total

1.  Primary spinal primitive neuroectodermal tumor: A single center series with literature review.

Authors:  Jun Ma; Shunchang Ma; Jun Yang; Guijun Jia; Wang Jia
Journal:  J Spinal Cord Med       Date:  2018-12-18       Impact factor: 1.985

Review 2.  Patterns of failure and optimal radiotherapy target volumes in primary intradural extramedullary Ewing sarcoma.

Authors:  Melanie A Chihak; Safia K Ahmed; Daniel H Lachance; Amulya A Nageswara Rao; Nadia N Laack
Journal:  Acta Oncol       Date:  2016-04-06       Impact factor: 4.089

Review 3.  Dumbbell-shaped peripheral primitive neuroectodermal tumor of the spine--case report and review of the literature.

Authors:  Lumír Hrabálek; Ondrej Kalita; Hana Svebisova; Jiri Ehrmann; Marian Hajduch; Radek Trojanec; Miroslav Kala
Journal:  J Neurooncol       Date:  2008-12-03       Impact factor: 4.130

4.  Peripheral primitive neuroectodermal tumor causing cauda equina syndrome with destruction of L5 vertebra.

Authors:  Sarvdeep Dhatt; Mandeep S Dhillon; Sujit K Tripathy; Tarun Goyal; V Jagadeesh
Journal:  Indian J Orthop       Date:  2010-07       Impact factor: 1.251

5.  Primary spinal extradural Ewing's sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature.

Authors:  Saeed Saeedinia; Mohsen Nouri; Meysam Alimohammadi; Hedieh Moradi; Abbas Amirjamshidi
Journal:  Surg Neurol Int       Date:  2012-05-14

6.  Intraspinal primitive neuroectodermal tumor in a man with neurofibromatosis type 1: Case report and review of the literature.

Authors:  Celene B Mulholland; Garni Barkhoudarian; Marcia E Cornford; Duncan Q McBride
Journal:  Surg Neurol Int       Date:  2011-10-29

7.  Primary dorsal spine primitive neuroectodermal tumor in an adult patient: Case report and literature review.

Authors:  Satyashiva Munjal; Amit Srivastava; Shivya Tucker; Neha Bakshi; Sunita Bhalla; V S Mehta
Journal:  J Craniovertebr Junction Spine       Date:  2017 Oct-Dec
  7 in total

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