Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 An efficient genetic screen in Drosophila to identify nuclear-encoded genes with mitochondrial function.

Literature DB >> 16849596

An efficient genetic screen in Drosophila to identify nuclear-encoded genes with mitochondrial function.

T S Vivian Liao¹, Gerald B Call, Preeta Guptan, Albert Cespedes, Jamie Marshall, Kevin Yackle, Edward Owusu-Ansah, Sudip Mandal, Q Angela Fang, Gelsey L Goodstein, William Kim, Utpal Banerjee.

Abstract

We conducted a screen for glossy-eye flies that fail to incorporate BrdU in the third larval instar eye disc but exhibit normal neuronal differentiation and isolated 23 complementation groups of mutants. These same phenotypes were previously seen in mutants for cytochrome c oxidase subunit Va. We have molecularly characterized six complementation groups and, surprisingly, each encodes a mitochondrial protein. Therefore, we believe our screen to be an efficient method for identifying genes with mitochondrial function.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2006 PMID： 16849596 PMCID： PMC1569793 DOI： 10.1534/genetics.106.061705

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

29 in total

1. An internal targeting signal directing proteins into the mitochondrial intermembrane space.

Authors: K Diekert; G Kispal; B Guiard; R Lill
Journal: Proc Natl Acad Sci U S A Date: 1999-10-12 Impact factor: 11.205

Review 2. The second stalk of Escherichia coli ATP synthase.

Authors: S D Dunn; D T McLachlin; M Revington
Journal: Biochim Biophys Acta Date: 2000-05-31

3. Combinatorial signaling in the specification of unique cell fates.

Authors: G V Flores; H Duan; H Yan; R Nagaraj; W Fu; Y Zou; M Noll; U Banerjee
Journal: Cell Date: 2000-09-29 Impact factor: 41.582

Review 4. Versatility of the mitochondrial protein import machinery.

Authors: N Pfanner; A Geissler
Journal: Nat Rev Mol Cell Biol Date: 2001-05 Impact factor: 94.444

Review 5. Mitochondria: releasing power for life and unleashing the machineries of death.

Authors: Donald D Newmeyer; Shelagh Ferguson-Miller
Journal: Cell Date: 2003-02-21 Impact factor: 41.582

Review 6. Function, structure, and biogenesis of mitochondrial ATP synthase.

Authors: Sharon H Ackerman; Alexander Tzagoloff
Journal: Prog Nucleic Acid Res Mol Biol Date: 2005

7. Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila.

Authors: Sudip Mandal; Preeta Guptan; Edward Owusu-Ansah; Utpal Banerjee
Journal: Dev Cell Date: 2005-12 Impact factor: 12.270

Review 8. Molecular mechanisms of cytochrome c biogenesis: three distinct systems.

Authors: R Kranz; R Lill; B Goldman; G Bonnard; S Merchant
Journal: Mol Microbiol Date: 1998-07 Impact factor: 3.501

9. The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.

Authors: A C Spradling; D Stern; A Beaton; E J Rhem; T Laverty; N Mozden; S Misra; G M Rubin
Journal: Genetics Date: 1999-09 Impact factor: 4.562

10. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.

Authors: T P Newsome; B Asling; B J Dickson
Journal: Development Date: 2000-02 Impact factor: 6.868

20 in total

1. De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment.

Authors: Debdeep Dutta; Lauren C Briere; Oguz Kanca; Paul C Marcogliese; Melissa A Walker; Frances A High; Adeline Vanderver; Joel Krier; Nikkola Carmichael; Christine Callahan; Ryan J Taft; Cas Simons; Guy Helman; Undiagnosed Diseases Network; Michael F Wangler; Shinya Yamamoto; David A Sweetser; Hugo J Bellen
Journal: Hum Mol Genet Date: 2020-06-03 Impact factor: 6.150

Review 2. Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases.

Authors: Shane L Rea; Brett H Graham; Eiko Nakamaru-Ogiso; Adwitiya Kar; Marni J Falk
Journal: Dev Disabil Res Rev Date: 2010

3. Mutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in Drosophila.

Authors: Wensheng Liu; Radhakrishnan Gnanasambandam; Jeffery Benjamin; Gunisha Kaur; Patricia B Getman; Alan J Siegel; Randall D Shortridge; Satpal Singh
Journal: Genetics Date: 2007-04-15 Impact factor: 4.562

4. "Deconstructing" scientific research: a practical and scalable pedagogical tool to provide evidence-based science instruction.

Authors: Ira E Clark; Rafael Romero-Calderón; John M Olson; Leslie Jaworski; David Lopatto; Utpal Banerjee
Journal: PLoS Biol Date: 2009-12-22 Impact factor: 8.029

5. Dystroglycan and mitochondrial ribosomal protein L34 regulate differentiation in the Drosophila eye.

Authors: Yougen Zhan; Nadia Y Melian; Mario Pantoja; Nicola Haines; Hannele Ruohola-Baker; Charles W Bourque; Yong Rao; Salvatore Carbonetto
Journal: PLoS One Date: 2010-05-05 Impact factor: 3.240

6. The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry.

Authors: Fionnuala Morrish; Nicola Neretti; John M Sedivy; David M Hockenbery
Journal: Cell Cycle Date: 2008-02-08 Impact factor: 4.534

7. Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila.

Authors: Francesca Di Cara; Edward Duca; Donald R Dunbar; Gerard Cagney; Margarete M S Heck
Journal: J Cell Sci Date: 2013-08-13 Impact factor: 5.285