| Literature DB >> 16846038 |
Shigeaki Ishizaka1, Yukiteru Ouji, Masahide Yoshikawa, Kazuki Nakatani.
Abstract
From a therapeutic perspective on liver, the use of embryonic stem (ES) technology in the generation of a large number of high-functional hepatocytes developed from ES cells for cell transplantation is anticipated. We have explored a three-dimensional culture system in which hepatocytes differentiated from mouse ES cells by transfection with the hepatocyte nuclear factor-3beta possess high metabolic functions that can be maintained long term.Entities:
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Year: 2006 PMID: 16846038 DOI: 10.1385/1-59745-036-7:387
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745