| Literature DB >> 16846027 |
Lijuan L Shang1, Samuel C Dudley, Arnold E Pfahnl.
Abstract
By directed differentiation using the hanging drop method, cardiomyocytes (CMs) can be derived from mouse embryonic stem cells. These spontaneously active CMs can then be isolated from the embryoid bodies and studied electrophysiologically for analysis of arrhythmic potential. This method is particularly advantangeous for studying CMs derived from genetically modified stem cells, in which mutations result in embryonic lethality.Entities:
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Year: 2006 PMID： 16846027 DOI： 10.1385/1-59745-036-7:221
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745