Literature DB >> 16845151

Avian flu: the wrath of birdzilla or Polly got the sniffles?

Tiffany Musick1, Holly Cymet, Tyler Childs Cymet.   

Abstract

The potential damage from an avian flu epidemic is huge, but unlikely. Currently, the virus affects birds and humans who handle dead birds. Only one case of suspected human-to-human transmission exists. If human-to-human transmission can occur with a new strain of the virus, we are susceptible to a pandemic. The many subtypes of influenza act and develop differently. The inflammatory response generated by the virus accounts for the illness. Vaccines are being developed, but the difficulties are real, and the time to success cannot be confidently stated. Lymphopenia, thrombocytopenia, and elevated liver enzymes are common. Treatment has to take into account societal issues as well as the individual health of every patient.

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Year:  2006        PMID: 16845151      PMCID: PMC7102272          DOI: 10.1385/comp:32:2:90

Source DB:  PubMed          Journal:  Compr Ther        ISSN: 0098-8243


  8 in total

Review 1.  Avian influenza A (H5N1) infection in humans.

Authors:  John H Beigel; Jeremy Farrar; Aye Maung Han; Frederick G Hayden; Randy Hyer; Menno D de Jong; Sorasak Lochindarat; Thi Kim Tien Nguyen; Tran Hien Nguyen; Tinh Hien Tran; Angus Nicoll; Sok Touch; Kwok-Yung Yuen
Journal:  N Engl J Med       Date:  2005-09-29       Impact factor: 91.245

2.  Avian influenza viruses and their implication for human health.

Authors:  Donald Kaye; Craig R Pringle
Journal:  Clin Infect Dis       Date:  2004-12-07       Impact factor: 9.079

3.  Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals.

Authors:  Taronna R Maines; Xui Hua Lu; Steven M Erb; Lindsay Edwards; Jeannette Guarner; Patricia W Greer; Doan C Nguyen; Kristy J Szretter; Li-Mei Chen; Pranee Thawatsupha; Malinee Chittaganpitch; Sunthareeya Waicharoen; Diep T Nguyen; Tung Nguyen; Hanh H T Nguyen; Jae-Hong Kim; Long T Hoang; Chun Kang; Lien S Phuong; Wilina Lim; Sherif Zaki; Ruben O Donis; Nancy J Cox; Jacqueline M Katz; Terrence M Tumpey
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

4.  p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1.

Authors:  Davy C W Lee; Chung-Yan Cheung; Anna H Y Law; Chris K P Mok; Malik Peiris; Allan S Y Lau
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

5.  Acylation-mediated membrane anchoring of avian influenza virus hemagglutinin is essential for fusion pore formation and virus infectivity.

Authors:  Ralf Wagner; Astrid Herwig; Nahid Azzouz; Hans Dieter Klenk
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

6.  A child with avian influenza A (H5N1) infection.

Authors:  Kulkanya Chokephaibulkit; Mongkol Uiprasertkul; Pilaipan Puthavathana; Pimpanada Chearskul; Prasert Auewarakul; Scott F Dowell; Nirun Vanprapar
Journal:  Pediatr Infect Dis J       Date:  2005-02       Impact factor: 2.129

7.  Human and avian influenza viruses target different cell types in cultures of human airway epithelium.

Authors:  Mikhail N Matrosovich; Tatyana Y Matrosovich; Thomas Gray; Noel A Roberts; Hans-Dieter Klenk
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-15       Impact factor: 11.205

Review 8.  Confronting the avian influenza threat: vaccine development for a potential pandemic.

Authors:  Iain Stephenson; Karl G Nicholson; John M Wood; Maria C Zambon; Jacqueline M Katz
Journal:  Lancet Infect Dis       Date:  2004-08       Impact factor: 25.071

  8 in total

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