Literature DB >> 16844951

MTHFR 677TT genotype increases the risk for cervical artery dissections.

M Kloss1, T Wiest, S Hyrenbach, I Werner, M-L Arnold, C Lichy, C Grond-Ginsbach.   

Abstract

The methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism was studied in 174 German patients with cervical artery dissection (CAD). The results were compared with published data on 927 healthy German controls. In the series of patients, the frequency of T alleles and of TT carriers was slightly higher (13.8%) than among the healthy controls (10.6%). In patients with multiple dissections (n = 50), the proportion of TT carriers (18%) was found to be even higher and correlated with the number of events. The MTHFR C677T polymorphism was suggested to modify the risk for CAD.

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Year:  2006        PMID： 16844951      PMCID： PMC2077623          DOI： 10.1136/jnnp.2006.089730

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  11 in total

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2.  Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection.

Authors:  V Gallai; V Caso; M Paciaroni; G Cardaioli; E Arning; T Bottiglieri; L Parnetti
Journal:  Stroke       Date:  2001-03       Impact factor: 7.914

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Authors:  Carsten Konrad; Georg A Müller; Claus Langer; Gregor Kuhlenbäumer; Klaus Berger; Darius G Nabavi; Rainer Dziewas; Florian Stögbauer; Erich B Ringelstein; Ralf Junker
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Journal:  Stroke       Date:  2002-03       Impact factor: 7.914

Review 7.  Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.

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  6 in total

1.  MTHFR 677 TT genotype and hyperhomocysteinaemia: an underestimated risk TANDEM for patients with stroke.

Authors:  V Caso; M Paciaroni
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-06-16       Impact factor: 10.154

2.  [Pain as sole symptom of carotid artery dissection].

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Journal:  Schmerz       Date:  2007-04       Impact factor: 1.107

3.  A narrative review of pathophysiological mechanisms associated with cervical artery dissection.

Authors:  Michael Haneline; Gary N Lewkovich
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4.  TGFBR2 mutation and MTHFR-C677T polymorphism in a Mexican mestizo population with cervico-cerebral artery dissection.

Authors:  Angélica Ruiz-Franco; Miguel A Barboza; Aurelio Jara-Prado; Samuel Canizales-Quinteros; Paola Leon-Mimila; Nayelli Arguelles-Morales; Juan-Camilo Vargas-González; Alejandro Quiroz-Compean; Antonio Arauz
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5.  The etiology of cervical artery dissection.

Authors:  Michael T Haneline; Anthony L Rosner
Journal:  J Chiropr Med       Date:  2007-09

6.  The migraine-ischemic stroke relation in young adults.

Authors:  Alessandro Pezzini; Elisabetta Del Zotto; Alessia Giossi; Irene Volonghi; Paolo Costa; Giorgio Dalla Volta; Alessandro Padovani
Journal:  Stroke Res Treat       Date:  2010-12-09
  6 in total

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