Literature DB >> 1684263

A study of the genomic diversity of Plasmodium falciparum in Senegal. 2. Typing by the use of the polymerase chain reaction.

O Mercereau-Puijalon1, T Fandeur, S Bonnefoy, C Jacquemot, J L Sarthou.   

Abstract

The genomic polymorphism of Plasmodium falciparum was investigated in a series of samples collected in Senegal during one transmission season. PCR analysis was performed on several genes coding for blood-stage antigens: the gene for the major merozoite surface antigen P190, the gene for the second merozoite surface antigen MSA2 and the gene coding for antigen 96tR/GBP130. In each case, several distinct forms of the genes studied were observed. Both the MAD20 and K1 allelic families of P190 genes were observed. PCR analysis of a single variable region did not differentiate each isolate. However, when the data obtained for several markers are combined, each isolate had a specific genotype. Thus, using PCR to study in parallel several loci is a useful tool to genetically type strains.

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Year:  1991        PMID： 1684263     DOI： 10.1016/0001-706x(91)90080-4

Source DB:  PubMed          Journal:  Acta Trop        ISSN： 0001-706X            Impact factor:   3.112


  7 in total

1.  A primary malarial infection is composed of a very wide range of genetically diverse but related parasites.

Authors:  P Druilhe; P Daubersies; J Patarapotikul; C Gentil; L Chene; T Chongsuphajaisiddhi; S Mellouk; G Langsley
Journal:  J Clin Invest       Date:  1998-05-01       Impact factor: 14.808

2.  Malarial Infection and Curable Sexually Transmitted and Reproductive Tract Infections Among Pregnant Women in a Rural District of Zambia.

Authors:  Enesia Banda Chaponda; R Matthew Chico; Jane Bruce; Charles Michelo; Bellington Vwalika; Sungano Mharakurwa; Mike Chaponda; James Chipeta; Daniel Chandramohan
Journal:  Am J Trop Med Hyg       Date:  2016-09-26       Impact factor: 2.345

3.  Development of a Plasmodium PCR for monitoring efficacy of antimalarial treatment.

Authors:  L Ciceron; G Jaureguiberry; F Gay; M Danis
Journal:  J Clin Microbiol       Date:  1999-01       Impact factor: 5.948

4.  PCR typing of field isolates of Plasmodium falciparum.

Authors:  H Contamin; T Fandeur; S Bonnefoy; F Skouri; F Ntoumi; O Mercereau-Puijalon
Journal:  J Clin Microbiol       Date:  1995-04       Impact factor: 5.948

5.  Cytoadherence and genotype of Plasmodium falciparum strains from symptomatic children in Franceville, southeastern Gabon.

Authors:  Fousseyni S Touré; Odile Ouwe-Missi-Oukem-Boyer; Jérôme Mezui-Me-Ndong; Guy Roger Ndong-Atome; Ulrick Bisvigou; Dominique Mazier; Sylvie Bisser
Journal:  Clin Med Res       Date:  2007-06

6.  High burden of malaria infection in pregnant women in a rural district of Zambia: a cross-sectional study.

Authors:  Enesia Banda Chaponda; Daniel Chandramohan; Charles Michelo; Sungano Mharakurwa; James Chipeta; R Matthew Chico
Journal:  Malar J       Date:  2015-09-30       Impact factor: 2.979

7.  Immune pressure selects for Plasmodium falciparum parasites presenting distinct red blood cell surface antigens and inducing strain-specific protection in Saimiri sciureus monkeys.

Authors:  T Fandeur; C Le Scanf; B Bonnemains; C Slomianny; O Mercereau-Puijalon
Journal:  J Exp Med       Date:  1995-01-01       Impact factor: 14.307
  7 in total

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