Literature DB >> 16842574

A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer.

N Ulger Toprak1, A Yagci, B M Gulluoglu, M L Akin, P Demirkalem, T Celenk, G Soyletir.   

Abstract

The prevalence of enterotoxigenic Bacteroides fragilis (ETBF) was investigated in stool specimens from 73 patients with colorectal cancer and from 59 control patients. Stool specimens were cultured on Bacteroides Bile Esculin agar and B. fragilis was identified by conventional methods. After DNA extraction, the enterotoxin gene (bft) was detected by PCR in 38% of the isolates from colorectal cancer patients, compared with 12% of the isolates from the control group (p 0.009). This is the first study demonstrating an increased prevalence of ETBF in colorectal cancer patients.

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Year:  2006        PMID： 16842574     DOI： 10.1111/j.1469-0691.2006.01494.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  166 in total

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