Literature DB >> 16842471

Significance of Rome II-defined functional constipation in Taiwan and comparison with constipation-predominant irritable bowel syndrome.

C-L Lu1, F-Y Chang, C-Y Chen, J-C Luo, S-D Lee.   

Abstract

BACKGROUND: The epidemiology and impact of functional constipation on Asians remain unclear. AIM: To determine the prevalence of functional constipation, its social/medical impact, and its distinction from constipation-predominant irritable bowel syndrome (C-IBS) in Taiwan.
METHODS: A Rome II questionnaire was administered to an apparently healthy adult Chinese population (n = 2865).
RESULTS: The prevalence of functional constipation was 8.5% and it was 2.7% for C-IBS. The functional constipation subjects were predominantly female and had excessive gastrointestinal-related doctor visits, absenteeism and sleep disturbance compared with controls (P < 0.01). Among functional constipation subjects, approximately 40% were 'consulters' with excessive doctor consultations, absenteeism and sleep disturbance. Female gender, the presence of sleep difficulty and higher constipation symptom scores were predictive of their consultation behaviour (P < 0.05). No differences existed in demographic variables, doctor consultations and absenteeism between 172 functional constipation and 54 C-IBS subjects. However, the C-IBS subjects experienced more severe constipation symptoms and sleep disturbance than functional constipation subjects.
CONCLUSIONS: Functional constipation in Taiwan is comparable with that in other countries. The clinical presentation of constipation-predominant irritable bowel syndrome differ somewhat from that of functional constipation.

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Year:  2006        PMID: 16842471     DOI: 10.1111/j.1365-2036.2006.02949.x

Source DB:  PubMed          Journal:  Aliment Pharmacol Ther        ISSN: 0269-2813            Impact factor:   8.171


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