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Literature DB >> 1684220

Alzheimer's disease. In the beginning...

D J Selkoe.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 1991 PMID： 1684220 DOI： 10.1038/354432a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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21 in total

1. Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.

Authors: Hyunbum Jang; Jie Zheng; Ruth Nussinov
Journal: Biophys J Date: 2007-05-25 Impact factor: 4.033

Review 2. Structural basis of infectious and non-infectious amyloids.

Authors: Ulrich Baxa
Journal: Curr Alzheimer Res Date: 2008-06 Impact factor: 3.498

3. Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels.

Authors: Hyunbum Jang; Fernando Teran Arce; Ricardo Capone; Srinivasan Ramachandran; Ratnesh Lal; Ruth Nussinov
Journal: Biophys J Date: 2009-12-02 Impact factor: 4.033

4. Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.

Authors: Joanne M Ajmo; Lauren A Bailey; Matthew D Howell; Lisa K Cortez; Keith R Pennypacker; Hina N Mehta; Dave Morgan; Marcia N Gordon; Paul E Gottschall
Journal: J Neurochem Date: 2010-02-17 Impact factor: 5.372

5. Molecular basis for amyloid-beta polymorphism.

Authors: Jacques-Philippe Colletier; Arthur Laganowsky; Meytal Landau; Minglei Zhao; Angela B Soriaga; Lukasz Goldschmidt; David Flot; Duilio Cascio; Michael R Sawaya; David Eisenberg
Journal: Proc Natl Acad Sci U S A Date: 2011-09-23 Impact factor: 11.205

6. In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging.

Authors: Yue Zhao; Marcus E Raichle; Jie Wen; Tammie L Benzinger; Anne M Fagan; Jason Hassenstab; Andrei G Vlassenko; Jie Luo; Nigel J Cairns; Jon J Christensen; John C Morris; Dmitriy A Yablonskiy
Journal: Neuroimage Date: 2016-12-15 Impact factor: 6.556

Alzheimer's disease. In the beginning...

1. Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.

Review 2. Structural basis of infectious and non-infectious amyloids.

3. Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels.

4. Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.

5. Molecular basis for amyloid-beta polymorphism.

6. In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging.

7. Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.

8. Structural convergence among diverse, toxic beta-sheet ion channels.

Review 9. Current pharmacotherapy and putative disease-modifying therapy for Alzheimer's disease.

Review 10. BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease.