Potential inroads to reducing hospital-acquired staphylococcal infection and its cost.

Staphylococci are still the most common agents implicated in hospital-acquired infections. In addition to Staphylococcus aureus, coagulase-negative staphylococci have attracted widespread interest, since they have emerged as the most frequent pathogen in foreign-body related infections. The emergence of methicillin-resistant S. aureus has resulted in increasing use of potentially toxic and extremely expensive antibiotics. To prevent hospital-acquired staphylococcal infections only control measures proven to be effective should be implemented and the cost of infection control procedures should always be considered. Handwashing as the simplest, cheapest, and still the most effective measure should constantly be stressed. In this article, effective procedures for the prevention of hospital-acquired staphylococcal infections are summarized, with special emphasis on cost-saving measures.