Literature DB >> 1684099

A molecular genetic linkage map of mouse chromosome 19, including the lpr, Ly-44, and Tdt genes.

T Watanabe1, Y Sakai, S Miyawaki, A Shimizu, O Koiwai, K Ohno.   

Abstract

The mouse lpr gene, which is an autosomal recessive gene causing autoimmune disease with features of human systemic lupus erythematosus and eventually death from severe immune-complex glomerulonephritis, has been mapped on chromosome 19. To determine its exact chromosomal location, a three-point backcross was carried out by mating (MRL/MpJ-lpr/lpr x MOL-MIT)F1 x MRL/MpJ-lpr/lpr using the genes Ly-44 (lymphocyte differentiation antigen-44) and Tdt (terminal deoxynucleotidyl transferase) as markers. The following order of genes is proposed, with the distances between genes given in parentheses: centromere-Ly-44 (19.3 cM)-lpr (6.1 cM)-Tdt-telomere. The Ly-44a and Tdta alleles are found in all laboratory strains and in the wild Western European subspecies, domesticus and brevirostris. In contrast, the Ly-44b and Tdtb alleles are found in some Asian subspecies, Chinese mice of wild origin, yamashinai and molossinus. Furthermore the third Tdt allele, Tdtc, is detected in castaneus.

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Year:  1991        PMID： 1684099     DOI： 10.1007/bf00554140

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  11 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Restriction fragment length polymorphism and chromosome mapping of a mouse homeo box gene, Hox-2.1.

Authors:  T Watanabe; S Masaki; N Takahashi; M Nishimura; H Kato
Journal:  Biochem Genet       Date:  1988-12       Impact factor: 1.890

3.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

4.  Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.

Authors:  T Glaser; K E Matthews; J W Hudson; P Seth; D E Housman; M M Crerar
Journal:  Genomics       Date:  1989-10       Impact factor: 5.736

5.  Restriction fragment length variations and chromosome mapping of two mouse metallothionein genes, Mt-1 and Mt-2.

Authors:  T Watanabe; A Shimizu; K Ohno; S Masaki; K Kondo
Journal:  Biochem Genet       Date:  1989-12       Impact factor: 1.890

6.  Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19.

Authors:  T F Tedder; G Klejman; C M Disteche; D A Adler; S F Schlossman; H Saito
Journal:  J Immunol       Date:  1988-12-15       Impact factor: 5.422

7.  Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Authors:  G M Wahl; M Stern; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

8.  A molecular genetic linkage map of mouse chromosome 18, including spm, Grl-1, Fim-2/c-fms, and Mbp.

Authors:  Y Sakai; S Miyawaki; A Shimizu; K Ohno; T Watanabe
Journal:  Biochem Genet       Date:  1991-02       Impact factor: 1.890

9.  Biochemical markers of three strains derived from Japanese wild mouse (Mus musculus molossinus).

Authors:  T Watanabe; T Ito; N Ogasawara
Journal:  Biochem Genet       Date:  1982-04       Impact factor: 1.890

10.  Mapping of the Hox-3.1 and Myc-1.2 genes on chromosome 15 of the mouse by restriction fragment length variations.

Authors:  T Watanabe; K Ohno; A Shimizu; Y Sakai; M Takahashi; N Takahashi
Journal:  Biochem Genet       Date:  1990-06       Impact factor: 1.890
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  13 in total

Review 1.  Anti-Sm autoantibodies in systemic lupus erythematosus mice: a model system for disease-specific autoreactivity.

Authors:  R A Eisenberg
Journal:  Springer Semin Immunopathol       Date:  1992

Review 2.  Mouse chromosome 19.

Authors:  J L Guénet; M Watson; M F Seldin
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  The Fas signaling connection between autoimmunity and embryonic lethality.

Authors:  H C Hsu; Y Matsuki; H G Zhang; T Zhou; J D Mountz
Journal:  J Clin Immunol       Date:  2001-01       Impact factor: 8.317

Review 4.  Mouse chromosome 19.

Authors:  J L Guénet
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  T cell repertoire and autoimmune diseases.

Authors:  L Imberti; A Sottini; D Primi
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

6.  A new allele at the lpr gene on mouse chromosome 19 expresses properties different from the original recessive mutation.

Authors:  T Watanabe; Y Sakai; A Hanai; S Masaki; K Ohno; S Miyawaki; A Matsuzawa
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

7.  Autoimmunity: twenty years in the Fas lane.

Authors:  Madhu Ramaswamy; Richard M Siegel
Journal:  J Immunol       Date:  2012-12-01       Impact factor: 5.422

8.  A molecular genetic linkage map of mouse chromosome 10, including the Myb, S100b, Pah, Sl, and Ifg genes.

Authors:  A Shimizu; Y Sakai; K Ohno; S Masaki; R Kuwano; Y Takahashi; N Miyashita; T Watanabe
Journal:  Biochem Genet       Date:  1992-10       Impact factor: 1.890

9.  Mapping of the mouse bilirubin UDP-glucuronosyltransferase gene (Gnt-1) to chromosome 1 by restriction fragment length variations.

Authors:  H Sato; Y Sakai; O Koiwai; T Watanabe
Journal:  Biochem Genet       Date:  1992-08       Impact factor: 1.890

10.  Differential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferase.

Authors:  N Doyen; M F d'Andon; L A Bentolila; Q T Nguyen; F Rougeon
Journal:  Nucleic Acids Res       Date:  1993-03-11       Impact factor: 16.971
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