| Literature DB >> 16839873 |
Douglas R Green1, Jerry E Chipuk.
Abstract
The p53 tumor suppressor pathway coordinates DNA repair, cell-cycle arrest, apoptosis, and senescence to preserve genomic stability and prevent tumor formation. The discovery of three new target genes for p53 reveals unexpected functions for this tumor suppressor in the regulation of glucose metabolism and autophagy.Entities:
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Year: 2006 PMID： 16839873 DOI： 10.1016/j.cell.2006.06.032
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582