| Literature DB >> 16839872 |
Abstract
A change in the shape of mitochondrial cristae must take place to attain rapid and complete release of cytochrome c during apoptosis. In this issue of Cell, Cipolat et al. and Frezza et al. (2006) show that a rhomboid intramembrane protease PARL and a dynamin-related protein OPA1 are critical regulators of cristae remodeling.Entities:
Mesh:
Substances:
Year: 2006 PMID: 16839872 DOI: 10.1016/j.cell.2006.06.030
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582