Literature DB >> 16839158

An expeditious enantioselective total synthesis of valilactone.

Yikang Wu1, Ya-Ping Sun.   

Abstract

The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic centers and a hydroxyl group activation (HGA) protocol to construct the anti alpha,beta-disubstituted beta-lactone from the corresponding syn aldol.

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Year:  2006        PMID： 16839158     DOI： 10.1021/jo060844m

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthesis of (+/-)- and (-)-vibralactone and vibralactone C.

Authors:  Quan Zhou; Barry B Snider
Journal:  J Org Chem       Date:  2008-09-19       Impact factor: 4.354

2.  Total Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species.

Authors:  Saniya S Khan; Thanuja D Sudasinghe; Alexander D Landgraf; Donald R Ronning; Steven J Sucheck
Journal:  ACS Infect Dis       Date:  2021-09-03       Impact factor: 5.578

3.  Synthesis of (+/-)-vibralactone.

Authors:  Quan Zhou; Barry B Snider
Journal:  Org Lett       Date:  2008-03-01       Impact factor: 6.005
  3 in total

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