Ventricular tachycardia originating from the epicardium identified by intracoronary mapping using a PTCA guidewire.

We report a case in which endocardial radiofrequency (RF) ablation guided by unipolar intracoronary mapping using a guidewire was an effective therapy for treating VT originating from an epicardial site of the left ventricle. A 55-year-old man with dilated cardiomyopathy was referred for treatment of refractory sustained monomorphic VT. The earliest unipolar electrogram with a near-perfect pace map was identified at segment #8 of the left anterior descending artery utilizing a guidewire through a microtube catheter during the VT. VT was terminated by an endocardial RF application at an upper midventricular septal site that did not have a good pacemap or the earliest electrogram, and that was the most adjacent anatomical endocardial site to the guidewire tip. No VT was clinically observed during a follow up period of 14 months.