| Literature DB >> 16836379 |
Emilia Modica1, Federica Compostella, Diego Colombo, Laura Franchini, Marco Cavallari, Lucia Mori, Gennaro De Libero, Luigi Panza, Fiamma Ronchetti.
Abstract
[Structure: see text] The C-sulfatide 1b was synthesized through a [2,3]-Wittig sigmatropic rearrangement and a Horner-Wadsworth-Emmons olefination as the key steps. The C-analogue 1b is less immunogenic than natural sulfatide 1a, but induces a preferential secretion of the proinflammatory cytokine IFN-gamma.Entities:
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Year: 2006 PMID： 16836379 DOI： 10.1021/ol061100y
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005