Literature DB >> 16835434

Touched and moved by STAT3.

S Paul Gao1, Jacqueline F Bromberg.   

Abstract

STAT3, a member of the signal transducer and activator of transcription (STAT) family of transcription factors, is a known regulator of cell motility through its transcriptional activating functions. However, new evidence suggests a novel role for non-tyrosine-phosphorylated and cytoplasmically localized STAT3 in mediating cell migration by disrupting an interaction between microtubules and one of its partners, stathmin. The association of STAT3 with stathmin potentiates microtubule polymerization and cell movement.

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Year:  2006        PMID： 16835434     DOI： 10.1126/stke.3432006pe30

Source DB:  PubMed          Journal:  Sci STKE        ISSN： 1525-8882


  41 in total

1.  Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.

Authors:  Utpal K Mukhopadhyay; Patrick Mooney; Lilly Jia; Robert Eves; Leda Raptis; Alan S Mak
Journal:  Mol Cell Biol       Date:  2010-08-23       Impact factor: 4.272

Review 2.  p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells.

Authors:  Alan S Mak
Journal:  Cell Adh Migr       Date:  2011-03-01       Impact factor: 3.405

3.  JAK/STAT: the enigma within the mystery of NMDAR-LTD.

Authors:  Todd C Sacktor
Journal:  Neuron       Date:  2012-01-26       Impact factor: 17.173

4.  FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.

Authors:  Ai-Hua Gong; Ping Wei; Sicong Zhang; Jun Yao; Ying Yuan; Ai-Dong Zhou; Frederick F Lang; Amy B Heimberger; Ganesh Rao; Suyun Huang
Journal:  Cancer Res       Date:  2015-04-01       Impact factor: 12.701

5.  The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis.

Authors:  R T Nitta; C A Del Vecchio; A H Chu; S S Mitra; A K Godwin; A J Wong
Journal:  Oncogene       Date:  2010-09-27       Impact factor: 9.867

6.  Upregulation of STAT3 marks Burkitt lymphoma cells refractory to Epstein-Barr virus lytic cycle induction by HDAC inhibitors.

Authors:  Derek Daigle; Cynthia Megyola; Ayman El-Guindy; Lyn Gradoville; David Tuck; George Miller; Sumita Bhaduri-McIntosh
Journal:  J Virol       Date:  2009-11-04       Impact factor: 5.103

7.  IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells.

Authors:  Minghua Zou; Xianquan Zhang; Changhua Xu
Journal:  Cell Oncol (Dordr)       Date:  2015-10-28       Impact factor: 6.730

8.  Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.

Authors:  Galina Gritsina; Fang Xiao; Shane W O'Brien; Rashid Gabbasov; Marisa A Maglaty; Ren-Huan Xu; Roshan J Thapa; Yan Zhou; Emmanuelle Nicolas; Samuel Litwin; Siddharth Balachandran; Luis J Sigal; Dennis Huszar; Denise C Connolly
Journal:  Mol Cancer Ther       Date:  2015-02-02       Impact factor: 6.261

9.  Role of STAT3 in in vitro transformation triggered by TRK oncogenes.

Authors:  Claudia Miranda; Tiziana Fumagalli; Maria Chiara Anania; Maria Grazia Vizioli; Sonia Pagliardini; Marco A Pierotti; Angela Greco
Journal:  PLoS One       Date:  2010-03-03       Impact factor: 3.240

10.  Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.

Authors:  Lesley A Mathews; Elaine M Hurt; Xiaohu Zhang; William L Farrar
Journal:  Mol Cancer       Date:  2010-10-07       Impact factor: 27.401
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