| Literature DB >> 16835082 |
Khalid Mohammed Khan1, Zafar S Saify, Muhammad Arif Lodhi, Naeem Butt, Shahnaz Perveen, Ghulam Murtaza Maharvi, Muhammad Iqbal Choudhary.
Abstract
A variety of piperidines (2-12, 14-26) with variable substituents at N-atoms have been synthesized and evaluated as urease inhibitors. The synthesized compounds showed varying degree of urease inhibitory activity ranging from 31.97 to 254 microM. The size and electron-donating or -withdrawing effects of substituents influence the activity, which lead to the formation of urease inhibitors.Entities:
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Year: 2006 PMID： 16835082 DOI： 10.1080/1478641500059383
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861