AIM: Retrospective analysis of male urethral carcinoma to assess the best therapeutic approach to the management of this tumor. METHODS: A review of 36 cases of male urethral carcinoma diagnosed and treated at our center was performed. Clinical features, treatment modality and outcomes were analysed. RESULTS: The overall median survival time was 55.16 months. The 5-year overall and disease-free survival rate for the cohort was 49% and 23%, respectively. The 5-year survival is 67% for low-stage versus 33% for high-stage tumors and is significantly different (P = 0.001). The survival was 72% for tumors of the distal urethra versus 36% for tumors of the proximal, with a P-value of 0.02. CONCLUSION: The tumor location and clinicopathological stage were the most important predictors of the disease-free and overall survival. Multimodal approach is necessary for achieving local control especially for proximal and higher stage tumors.
AIM: Retrospective analysis of male urethral carcinoma to assess the best therapeutic approach to the management of this tumor. METHODS: A review of 36 cases of male urethral carcinoma diagnosed and treated at our center was performed. Clinical features, treatment modality and outcomes were analysed. RESULTS: The overall median survival time was 55.16 months. The 5-year overall and disease-free survival rate for the cohort was 49% and 23%, respectively. The 5-year survival is 67% for low-stage versus 33% for high-stage tumors and is significantly different (P = 0.001). The survival was 72% for tumors of the distal urethra versus 36% for tumors of the proximal, with a P-value of 0.02. CONCLUSION: The tumor location and clinicopathological stage were the most important predictors of the disease-free and overall survival. Multimodal approach is necessary for achieving local control especially for proximal and higher stage tumors.
Authors: Farshid Dayyani; Curtis A Pettaway; Ashish M Kamat; Mark F Munsell; Kanishka Sircar; Lance C Pagliaro Journal: Urol Oncol Date: 2012-04-24 Impact factor: 3.498
Authors: Giuseppe Lucarelli; Marco Spilotros; Antonio Vavallo; Silvano Palazzo; Carlos Miacola; Saverio Forte; Matteo Matera; Marcello Campagna; Ottavio Colamonico; Francesco Schiralli; Francesco Sebastiani; Federica Di Cosmo; Carlo Bettocchi; Giuseppe Di Lorenzo; Carlo Buonerba; Leonardo Vincenti; Giuseppe Ludovico; Pasquale Ditonno; Michele Battaglia Journal: Medicine (Baltimore) Date: 2016-05 Impact factor: 1.889