| Literature DB >> 16834355 |
Vanessa Schmidt1, Cristiano Giacomelli, François Lecolley, Joséphine Lai-Kee-Him, Alain R Brisson, Redouane Borsali.
Abstract
The formation of protein-decorated nanosized polymeric particles is described. Annexin-A5 protein binding to micellar aggregates having poly((1-ethoxycarbonyl)vinylphosphonic diacid) (PECVPD) and poly(n-butyl acrylate) (PBuA) as corona- and core-forming segments, respectively, was evidenced by Static and Dynamic Light Scattering (SDLS), cryo-Transmission Electron Microscopy (cryo-TEM), and Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) experiments. These new objects find potential applications, for example, in micelle-mediated target drug delivery and controlled fabrication of biochips.Entities:
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Year: 2006 PMID： 16834355 DOI： 10.1021/ja062408n
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419