Literature DB >> 16833013

Synthesis and evaluation of biological properties of benzylideneacetophenone derivatives.

Seikwan Oh1, Soyong Jang, Donghyun Kim, Inn-Oc Han, Jae-Chul Jung.   

Abstract

A series of yakuchinone B 1f and its analogs 1a-e was synthesized and evaluated for free radical scavenging, suppression of LPS-induced NO generation, cytotoxicity and anti-excitotoxicity in vitro. Compound 1c exhibited potent anti-excitotoxicity, while all compounds 1a-f showed considerable effects of free radical scavenging, suppression of LPS-induced NO generation, and cytotoxicity in microglia.

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Year:  2006        PMID： 16833013     DOI： 10.1007/bf02969418

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  4 in total

1.  Antioxidant and free radical scavenging potential of yakuchinone B derivatives in reduction of lipofuscin formation using H2O2-treated neuroblastoma cells.

Authors:  Samaneh Bayati; Razieh Yazdanparast
Journal:  Iran Biomed J       Date:  2011

2.  Alleviation of Atopic Dermatitis Lesions by a Benzylideneacetophenone Derivative via the MAPK Signaling Pathway.

Authors:  Bongjun Sur; Seungmin Kang; Mijin Kim; Seikwan Oh
Journal:  Inflammation       Date:  2019-06       Impact factor: 4.092

3.  Benzylideneacetophenone derivatives attenuate IFN-γ-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition.

Authors:  Sung-Hee Lee; Seul Ye Lim; Ji Ha Choi; Jae-Chul Jung; Seikwan Oh; Koung Hoon Kook; Youn-Hee Choi
Journal:  Exp Mol Med       Date:  2014-06-13       Impact factor: 8.718

4.  Synthesis and Antioxidant Activity of Caffeic Acid Derivatives.

Authors:  Katarzyna Sidoryk; Anna Jaromin; Nina Filipczak; Piotr Cmoch; Marcin Cybulski
Journal:  Molecules       Date:  2018-08-30       Impact factor: 4.411
  4 in total

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