| Literature DB >> 16831296 |
M Marchisio1, V Bertagnolo, P Lanuti, A R Gaspari, M Paludi, F Ciccocioppo, E Ercolino, A Bascelli, A Cataldi, S Miscia.
Abstract
Protein kinase Cs (PKCs) belong to a serine/threonine kinase family, ubiquitously expressed and claimed to be involved in physiological processes including apoptosis, cell growth and differentiation. The question of the subcellular localization and activity of PKCs remains to be clarified. Here we report that nuclear PKC-delta cooperates to regulate the S-G2/M phase transition of cell cycle, apparently being associated to chromosome condensation and alignment on the metaphase plate.Entities:
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Year: 2006 PMID： 16831296 DOI： 10.1177/039463200601900206
Source DB: PubMed Journal: Int J Immunopathol Pharmacol ISSN： 0394-6320 Impact factor: 3.219