Literature DB >> 16829983

RNA-quality control by the exosome.

Jonathan Houseley1, John LaCava, David Tollervey.   

Abstract

The exosome complex of 3'-->5' exonucleases is an important component of the RNA-processing machinery in eukaryotes. This complex functions in the accurate processing of nuclear RNA precursors and in the degradation of RNAs in both the nucleus and the cytoplasm. However, it has been unclear how different classes of substrate are distinguished from one another. Recent studies now provide insights into the regulation and structure of the exosome, and they reveal striking similarities between the process of RNA degradation in bacteria and eukaryotes.

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Year:  2006        PMID： 16829983     DOI： 10.1038/nrm1964

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  317 in total

1.  RNA elimination machinery targeting meiotic mRNAs promotes facultative heterochromatin formation.

Authors:  Martin Zofall; Soichiro Yamanaka; Francisca E Reyes-Turcu; Ke Zhang; Chanan Rubin; Shiv I S Grewal
Journal:  Science       Date:  2011-12-01       Impact factor: 47.728

2.  The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Authors:  Rafal Tomecki; Maiken S Kristiansen; Søren Lykke-Andersen; Aleksander Chlebowski; Katja M Larsen; Roman J Szczesny; Karolina Drazkowska; Agnieszka Pastula; Jens S Andersen; Piotr P Stepien; Andrzej Dziembowski; Torben Heick Jensen
Journal:  EMBO J       Date:  2010-06-08       Impact factor: 11.598

Review 3.  The roles of TTP and BRF proteins in regulated mRNA decay.

Authors:  Sandhya Sanduja; Fernando F Blanco; Dan A Dixon
Journal:  Wiley Interdiscip Rev RNA       Date:  2011 Jan-Feb       Impact factor: 9.957

4.  Replication of avocado sunblotch viroid in the yeast Saccharomyces cerevisiae.

Authors:  Clémentine Delan-Forino; Marie-Christine Maurel; Claire Torchet
Journal:  J Virol       Date:  2011-01-26       Impact factor: 5.103

5.  A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi.

Authors:  Yinyan Sun; Peiguo Yang; Yuxia Zhang; Xin Bao; Jun Li; Wenru Hou; Xiangyu Yao; Jinghua Han; Hong Zhang
Journal:  Protein Cell       Date:  2011-12-17       Impact factor: 14.870

6.  The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2.

Authors:  Stéphanie Schillewaert; Ludivine Wacheul; Frédéric Lhomme; Denis L J Lafontaine
Journal:  Mol Cell Biol       Date:  2011-11-14       Impact factor: 4.272

7.  Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor.

Authors:  Alvaro Peña; Kamil Gewartowski; Seweryn Mroczek; Jorge Cuéllar; Aleksandra Szykowska; Andrzej Prokop; Mariusz Czarnocki-Cieciura; Jan Piwowarski; Cristina Tous; Andrés Aguilera; José L Carrascosa; José María Valpuesta; Andrzej Dziembowski
Journal:  EMBO J       Date:  2012-02-07       Impact factor: 11.598

8.  Sequential RNA degradation pathways provide a fail-safe mechanism to limit the accumulation of unspliced transcripts in Saccharomyces cerevisiae.

Authors:  Shakir Sayani; Guillaume F Chanfreau
Journal:  RNA       Date:  2012-07-02       Impact factor: 4.942

9.  Rrp6 is recruited to transcribed genes and accompanies the spliced mRNA to the nuclear pore.

Authors:  Viktoria Hessle; Anne von Euler; Ernesto González de Valdivia; Neus Visa
Journal:  RNA       Date:  2012-06-28       Impact factor: 4.942

10.  Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance.

Authors:  Nathan N Lee; Venkata R Chalamcharla; Francisca Reyes-Turcu; Sameet Mehta; Martin Zofall; Vanivilasini Balachandran; Jothy Dhakshnamoorthy; Nitika Taneja; Soichiro Yamanaka; Ming Zhou; Shiv I S Grewal
Journal:  Cell       Date:  2013-11-07       Impact factor: 41.582
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