Literature DB >> 16829502

Xerostomia and medications among 32-year-olds.

William Murray Thomson1, Richie Poulton, Jonathan Mark Broadbent, Shaima Al-Kubaisy.   

Abstract

OBJECTIVE: To describe the prevalence and associations of xerostomia among adults in their early thirties, with particular attention to medication exposure as a putative risk factor.
MATERIAL AND METHODS: The prevalence and associations of xerostomia were investigated among 32-year-old participants in a long-standing prospective cohort study. Some 950 individuals were assessed at ages 26 and 32 years, with medications being recorded on both occasions.
RESULTS: The prevalence of xerostomia was 10.0% (with no apparent gender difference), and was significantly higher among those taking antidepressants (odds ratio = 4.7), iron supplements (OR = 4.1) or narcotic analgesics (OR = 2.4). Those taking antidepressants at both ages 26 and 32 years had 22 times the odds of reporting xerostomia.
CONCLUSION: Xerostomia may be a problem for a sizeable minority of young adults.

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Year:  2006        PMID: 16829502      PMCID: PMC2249168          DOI: 10.1080/00016350600633243

Source DB:  PubMed          Journal:  Acta Odontol Scand        ISSN: 0001-6357            Impact factor:   2.331


  21 in total

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2.  Prevalence of perceived symptoms of dry mouth in an adult Swedish population--relation to age, sex and pharmacotherapy.

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3.  Subjective reports of xerostomia and objective measures of salivary gland performance.

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4.  Clinical features of burning mouth syndrome.

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Journal:  Oral Surg Oral Med Oral Pathol       Date:  1987-01

5.  The clinician's illusion.

Authors:  P Cohen; J Cohen
Journal:  Arch Gen Psychiatry       Date:  1984-12

6.  Mouth dryness among patients in longterm hospitals.

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7.  The occurrence of xerostomia and salivary gland hypofunction in a population-based sample of older South Australians.

Authors:  W M Thomson; J M Chalmers; A J Spencer; M Ketabi
Journal:  Spec Care Dentist       Date:  1999 Jan-Feb

8.  Clinical and physiological investigations in patients with taste abnormality.

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10.  Clinical study of patients with burning mouth.

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  20 in total

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Review 2.  World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction: prevalence, diagnosis, and treatment.

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3.  Evaluation of Xerostomia in Different Psychological Disorders: An Observational Study.

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4.  Addition of chocolate milk to diet corresponds to protein concentration changes in human saliva.

Authors:  Ciera R Crawford; Cordelia A Running
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5.  Oral health in patients taking psychotropic medications: Results from a pharmacy-based pilot study.

Authors:  Lisa J Heaton; Kimberly Swigart; Gavin McNelis; Peter Milgrom; Donald F Downing
Journal:  J Am Pharm Assoc (2003)       Date:  2016-06-03

6.  The Dunedin Multidisciplinary Health and Development Study: Oral health findings and their implications.

Authors:  C L Hong; J M Broadbent; W M Thomson; R Poulton
Journal:  J R Soc N Z       Date:  2020-02-04       Impact factor: 2.750

7.  Interventions for the treatment of xerostomia: A randomized controlled clinical trial.

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8.  The poor oral health status of former heroin users treated with methadone in a Chinese city.

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Journal:  Med Sci Monit       Date:  2012-04

9.  The diagnostic suitability of a xerostomia questionnaire and the association between xerostomia, hyposalivation and medication use in a group of nursing home residents.

Authors:  Gert-Jan van der Putten; Henk S Brand; Jos M G A Schols; Cees de Baat
Journal:  Clin Oral Investig       Date:  2010-02-18       Impact factor: 3.573

10.  Signs of oral dryness in relation to salivary flow rate, pH, buffering capacity and dry mouth complaints.

Authors:  Najat M A Farsi
Journal:  BMC Oral Health       Date:  2007-11-09       Impact factor: 2.757

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