Literature DB >> 16828767

Misoprostol and active management of the third stage of labor.

N Prata1, S Hamza, R Gypson, K Nada, F Vahidnia, M Potts.   

Abstract

OBJECTIVE: To compare current practices for the active management of the third stage of labor (AMTSL) with the use of 600 mug of oral misoprostol.
METHODS: An operations research study was designed to compare blood loss with current AMTSL practices and misoprostol use.
RESULTS: Women in the misoprostol group were less likely to bleed 500 ml or more (adjusted odds ratio, 0.30; 95% confidence interval, 0.16-0.56) compared with those in the current practices group. In the current practices group 73% women required interventions because of postpartum hemorrhage, compared with 11% in the misoprostol group.
CONCLUSION: In situations where oxytocin and or ergometrine are not consistently and appropriately used during third stage of labor, misoprostol should be considered for inclusion in the AMTSL protocol.

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Year:  2006        PMID: 16828767     DOI: 10.1016/j.ijgo.2006.05.027

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  7 in total

Review 1.  What measured blood loss tells us about postpartum bleeding: a systematic review.

Authors:  N L Sloan; J Durocher; T Aldrich; J Blum; B Winikoff
Journal:  BJOG       Date:  2010-04-20       Impact factor: 6.531

2.  Inability to predict postpartum hemorrhage: insights from Egyptian intervention data.

Authors:  Ndola Prata; Sabry Hamza; Suzanne Bell; Deborah Karasek; Farnaz Vahidnia; Martine Holston
Journal:  BMC Pregnancy Childbirth       Date:  2011-11-28       Impact factor: 3.007

3.  Stakeholder perceptions of misoprostol: a qualitative investigation.

Authors:  Alessandra N Bazzano; Lea Jones; Thoai D Ngo
Journal:  Int J Womens Health       Date:  2014-04-08

4.  Helping rural women in Pakistan to prevent postpartum hemorrhage: a quasi experimental study.

Authors:  Ali Mohammad Mir; Abdul Wajid; Sadaf Gull
Journal:  BMC Pregnancy Childbirth       Date:  2012-10-30       Impact factor: 3.007

5.  Feasibility, acceptability, and programme effectiveness of misoprostol for prevention of postpartum haemorrhage in rural bangladesh: a quasiexperimental study.

Authors:  Abdul Quaiyum; Rukhsana Gazi; Shahed Hossain; Andrea Wirtz; Nirod Chandra Saha
Journal:  Int J Reprod Med       Date:  2014-04-07

6.  Misoprostol for primary versus secondary prevention of postpartum haemorrhage: a cluster-randomised non-inferiority community trial.

Authors:  S Raghavan; S Geller; S Miller; S S Goudar; H Anger; M C Yadavannavar; R Dabash; S R Bidri; M R Gudadinni; R Udgiri; A R Koch; M B Bellad; B Winikoff
Journal:  BJOG       Date:  2015-09-01       Impact factor: 6.531

7.  Using Misoprostol for Primary versus Secondary Prevention of Postpartum Haemorrhage - Do Costs Matter?

Authors:  Susmita Chatterjee; Anupam Sarkar; Krishna D Rao
Journal:  PLoS One       Date:  2016-10-18       Impact factor: 3.240

  7 in total

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