| Literature DB >> 16828273 |
N Skivesen1, R Horvath, S Thinggaard, N B Larsen, H C Pedersen.
Abstract
Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150-200 nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection limit of 8-9 cells/mm2.Entities:
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Year: 2006 PMID: 16828273 DOI: 10.1016/j.bios.2006.05.025
Source DB: PubMed Journal: Biosens Bioelectron ISSN: 0956-5663 Impact factor: 10.618