| Literature DB >> 1682739 |
J E Taylor1, I S Henderson, W K Stewart, J J Belch.
Abstract
Erythropoietin significantly, reversibly, and reproducibly increased in-vitro whole-blood spontaneous platelet aggregation in 15 patients on haemodialysis. During erythropoietin treatment, spontaneous platelet aggregation was significantly higher in these subjects than in non-uraemic controls; concomitant treatment with 300 mg aspirin daily reversed platelet hyperaggregability. Erythropoietin may promote thrombosis by an effect on platelet function.Entities:
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Year: 1991 PMID: 1682739 DOI: 10.1016/0140-6736(91)92239-x
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321