| Literature DB >> 16826979 |
A Jha1, J R Dimmock.
Abstract
Various acyl groups possessing markedly divergent topography were placed on the nitrogen atom of the antimycobacterial agent 3,5-bis(phenylmethylene)-4-piperidone (1). Some of the N-maleamoyl analogues of 1 displayed antitubercular properties thereby affording an insight into the structural requirements for interactions at a putative auxiliary binding site in the bacterium.Entities:
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Year: 2006 PMID： 16826979
Source DB: PubMed Journal: Pharmazie ISSN： 0031-7144 Impact factor: 1.267