Literature DB >> 16826389

The Mucus Slurper: A novel tracheal tube that requires no tracheal tube suctioning. A preliminary report.

Theodor Kolobow1, Gianluigi Li Bassi, Francesco Curto, Alberto Zanella.   

Abstract

OBJECTIVE: The buildup of mucus within the endotracheal tube (ETT) progressively reduces its internal volume. We devised the Mucus Slurper as an integral part of the tracheal tube to aspirate all mucus automatically at its distal tip. DESIGN AND
SETTING: In vitro, and in vivo studies in sheep at the National Institutes of Health, NHLBI, PCCMB.
SUBJECTS: Six sheep, sedated, paralyzed, and mechanically ventilated
INTERVENTIONS: We evaluated the Mucus Slurper in vitro, and we evaluated its efficacy and safety in three healthy sheep during 24 h on volume-controlled mechanical ventilation in comparison to three sheep managed with open tracheal tube suctioning. MEASUREMENTS AND
RESULTS: In vitro: with the Mucus Slurper connected to a source of vacuum of 450-500 mmHg the total volume of a single suction lasting 0.1, 0.2, and 0.3 s was, respectively, 75.4 +/- 7.9, 114.5 +/- 4.6, and 143.4 +/- 8.7 ml; with the measured vacuum within the lumen of the Mucus Slurper ring of 37 cmH2O. In vivo: during mechanical ventilation we aspirated through the Mucus Slurper 13.4 +/- 3.3 cc mucus/24 h. During the course of single aspiration the Mucus Slurper never affected the level of applied PEEP. The tracheal tube was free of tracheal secretions in the Mucus Slurper group while thin secretions were found within the ETT in the control group.
CONCLUSION: The Mucus Slurper is a novel device designed to keep the tracheal tube and proximal trachea free of mucus. In studies in sheep lasting 24 h the Mucus Slurper was safe and prevented all mucus accumulation within the ETT.

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Year:  2006        PMID: 16826389     DOI: 10.1007/s00134-006-0268-5

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  6 in total

1.  Glottic-modulated lung ventilation during continuous transtracheal gas insufflation: an experimental study.

Authors:  Nicolo Patroniti; Muriel Verweij; Theodor Kolobow
Journal:  Crit Care Med       Date:  2003-05       Impact factor: 7.598

2.  AARC clinical practice guideline. Endotracheal suctioning of mechanically ventilated adults and children with artificial airways. American Association for Respiratory Care.

Authors: 
Journal:  Respir Care       Date:  1993-05       Impact factor: 2.258

3.  Novel system for complete removal of secretions within the endotracheal tube: the Mucus Shaver.

Authors:  Theodor Kolobow; Lorenzo Berra; Gianluigi Li Bassi; Francesco Curto
Journal:  Anesthesiology       Date:  2005-05       Impact factor: 7.892

4.  Bacterial colonization of the respiratory tract following tracheal intubation-effect of gravity: an experimental study.

Authors:  M Panigada; L Berra; G Greco; M Stylianou; T Kolobow
Journal:  Crit Care Med       Date:  2003-03       Impact factor: 7.598

5.  Prevention of endotracheal suctioning-induced alveolar derecruitment in acute lung injury.

Authors:  Salvatore M Maggiore; Francois Lellouche; Jerome Pigeot; Solenne Taille; Nicolas Deye; Xavier Durrmeyer; Jean-Christophe Richard; Jordi Mancebo; Francois Lemaire; Laurent Brochard
Journal:  Am J Respir Crit Care Med       Date:  2003-02-13       Impact factor: 21.405

6.  Guidelines for preventing health-care--associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee.

Authors:  Ofelia C Tablan; Larry J Anderson; Richard Besser; Carolyn Bridges; Rana Hajjeh
Journal:  MMWR Recomm Rep       Date:  2004-03-26
  6 in total
  4 in total

Review 1.  Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal failure and endocrinology.

Authors:  Peter Andrews; Elie Azoulay; Massimo Antonelli; Laurent Brochard; Christian Brun-Buisson; Daniel De Backer; Geoffrey Dobb; Jean-Yves Fagon; Herwig Gerlach; Johan Groeneveld; Duncan Macrae; Jordi Mancebo; Philipp Metnitz; Stefano Nava; Jerôme Pugin; Michael Pinsky; Peter Radermacher; Christian Richard
Journal:  Intensive Care Med       Date:  2006-12-19       Impact factor: 17.440

Review 2.  Technologic advances in endotracheal tubes for prevention of ventilator-associated pneumonia.

Authors:  Juan F Fernandez; Stephanie M Levine; Marcos I Restrepo
Journal:  Chest       Date:  2012-07       Impact factor: 9.410

3.  A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions.

Authors:  Lorenzo Berra; Andrea Coppadoro; Edward A Bittner; Theodor Kolobow; Patrice Laquerriere; Joshua R Pohlmann; Simone Bramati; Joel Moss; Antonio Pesenti
Journal:  Crit Care Med       Date:  2012-01       Impact factor: 7.598

4.  Internally coated endotracheal tubes with silver sulfadiazine in polyurethane to prevent bacterial colonization: a clinical trial.

Authors:  Lorenzo Berra; Theodor Kolobow; Patrice Laquerriere; Betsey Pitts; Simone Bramati; Joshua Pohlmann; Chiara Marelli; Miriam Panzeri; Pietro Brambillasca; Federico Villa; Andrea Baccarelli; Sylvie Bouthors; Henry T Stelfox; Luca M Bigatello; Joel Moss; Antonio Pesenti
Journal:  Intensive Care Med       Date:  2008-04-17       Impact factor: 17.440

  4 in total

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