Literature DB >> 16825907

Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding.

Emilio Estévez1, Benito González-Conde, José Luis Vázquez-Iglesias, Maria de Los Angeles Vázquez-Millán, Sonia Pértega, Pedro A Alonso, Joan Clofent, Eva Santos, José Luis Ulla, Eloy Sánchez.   

Abstract

OBJECTIVES: The endoscopic capsule is a useful tool for visualizing the small bowel in patients with obscure gastrointestinal bleeding. In this study the authors evaluated the diagnostic aid provided by the endoscopic capsule, the factors predicting a significant finding and their impact on the patients' clinical evolution.
METHODS: A total of 100 patients (52 men and 48 women, average age 64.4 years) underwent capsule endoscopy. Of this group, 52 patients presented with obscure-overt bleeding and 48 with obscure-occult bleeding. After an average follow-up time of 11.4 months, the clinical outcome was evaluated in 95 patients.
RESULTS: The endoscopic capsule identified significant findings in 68% of patients. The most common diagnosis (33.8%) was angiodysplasias. The most important factor predicting significant findings was the previous need for transfusion in the overt bleeding group. As the result of the findings, a specific intervention was made in 75.8% of patients. At the end of follow-up, the clinical outcome was considered positive in 71.6% of patients. Capsule retention occurred in one patient, who required surgery.
CONCLUSION: In patients with obscure gastrointestinal bleeding, capsule endoscopy provides a high degree of diagnostic aid. The best candidates for this procedure are patients with obscure-overt bleeding who have required blood transfusions. Capsule endoscopy has a positive influence on an important proportion of patients, whether oriented towards new diagnostic techniques or towards a definitive treatment.

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Year:  2006        PMID: 16825907     DOI: 10.1097/00042737-200608000-00014

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  22 in total

1.  Therapeutic management options for patients with obscure gastrointestinal bleeding.

Authors:  Gursimran S Kochhar; Madhusudhan R Sanaka; John J Vargo
Journal:  Therap Adv Gastroenterol       Date:  2012-01       Impact factor: 4.409

Review 2.  Small bowel capsule endoscopy in 2007: indications, risks and limitations.

Authors:  Emanuele Rondonotti; Federica Villa; Chris J J Mulder; Maarten A J M Jacobs; Roberto de Franchis
Journal:  World J Gastroenterol       Date:  2007-12-14       Impact factor: 5.742

Review 3.  Role of small bowel capsule endoscopy in the diagnosis and management of iron deficiency anemia in elderly: a comprehensive review of the current literature.

Authors:  Adnan Muhammad; Gitanjali Vidyarthi; Patrick Brady
Journal:  World J Gastroenterol       Date:  2014-07-14       Impact factor: 5.742

Review 4.  Continuing challenges in the diagnosis and management of obscure gastrointestinal bleeding.

Authors:  Veronica Baptista; Neil Marya; Anupam Singh; Abbas Rupawala; Bilal Gondal; David Cave
Journal:  World J Gastrointest Pathophysiol       Date:  2014-11-15

Review 5.  Performance measures for small-bowel endoscopy: A European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative.

Authors:  Cristiano Spada; Deirdre McNamara; Edward J Despott; Samuel Adler; Brooks D Cash; Ignacio Fernández-Urién; Hrvoje Ivekovic; Martin Keuchel; Mark McAlindon; Jean-Christophe Saurin; Simon Panter; Cristina Bellisario; Silvia Minozzi; Carlo Senore; Cathy Bennett; Michael Bretthauer; Mario Dinis-Ribeiro; Dirk Domagk; Cesare Hassan; Michal F Kaminski; Colin J Rees; Roland Valori; Raf Bisschops; Matthew D Rutter
Journal:  United European Gastroenterol J       Date:  2019-05-15       Impact factor: 4.623

6.  Efficacy of computed image modification of capsule endoscopy in patients with obscure gastrointestinal bleeding.

Authors:  Tomoaki Matsumura; Makoto Arai; Toru Sato; Tomoo Nakagawa; Daisuke Maruoka; Masaru Tsuboi; Sachio Hata; Eiji Arai; Tatsuro Katsuno; Fumio Imazeki; Osamu Yokosuka
Journal:  World J Gastrointest Endosc       Date:  2012-09-16

Review 7.  Occult and obscure gastrointestinal bleeding: causes and clinical management.

Authors:  Don C Rockey
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-03-30       Impact factor: 46.802

Review 8.  Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding.

Authors:  Georgios Tziatzios; Paraskevas Gkolfakis; George D Dimitriadis; Konstantinos Triantafyllou
Journal:  Ann Transl Med       Date:  2017-05

9.  Factors associated with the clinical impact of capsule endoscopy in patients with overt obscure gastrointestinal bleeding.

Authors:  Motohiro Esaki; Takayuki Matsumoto; Shinichiro Yada; Ritsuko Yanaru-Fujisawa; Tetsuji Kudo; Shunichi Yanai; Shotaro Nakamura; Mitsuo Iida
Journal:  Dig Dis Sci       Date:  2009-12-03       Impact factor: 3.199

10.  Long-term impact of capsule endoscopy in patients referred for iron-deficiency anemia.

Authors:  Sarah Sheibani; Barrett G Levesque; Shai Friedland; Jennifer Roost; Lauren B Gerson
Journal:  Dig Dis Sci       Date:  2009-11-26       Impact factor: 3.199

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