BACKGROUND AND AIM: Kangaroo mother care (KMC) has become the standard of care for low-risk preterm babies born in developing countries. However, the potential risk of nosocomial transmission of Mycobacterium tuberculosis within KMC units, particularly in tuberculosis-endemic areas, has not been explored. We report an infant (sentinel case) who was admitted to our paediatric intensive care unit (PICU) with extensive pulmonary tuberculosis. METHODS AND RESULTS: When interviewed, the mother reported no household contact with a tuberculosis source case, but mentioned that she shared a KMC room with someone who had symptoms suspicious of tuberculosis. We found molecular evidence that nosocomial transmission of M. tuberculosis occurred within the KMC unit and conducted a contact investigation of all infants exposed to this infectious source case during her stay in the KMC unit. CONCLUSION: We present the findings of the contact investigation and discuss the implications of these findings for KMC units, particularly in tuberculosis-endemic areas.
BACKGROUND AND AIM: Kangaroo mother care (KMC) has become the standard of care for low-risk preterm babies born in developing countries. However, the potential risk of nosocomial transmission of Mycobacterium tuberculosis within KMC units, particularly in tuberculosis-endemic areas, has not been explored. We report an infant (sentinel case) who was admitted to our paediatric intensive care unit (PICU) with extensive pulmonary tuberculosis. METHODS AND RESULTS: When interviewed, the mother reported no household contact with a tuberculosis source case, but mentioned that she shared a KMC room with someone who had symptoms suspicious of tuberculosis. We found molecular evidence that nosocomial transmission of M. tuberculosis occurred within the KMC unit and conducted a contact investigation of all infants exposed to this infectious source case during her stay in the KMC unit. CONCLUSION: We present the findings of the contact investigation and discuss the implications of these findings for KMC units, particularly in tuberculosis-endemic areas.
Authors: André G Loxton; Julia K Knaul; Leander Grode; Andrea Gutschmidt; Christiane Meller; Bernd Eisele; Hilary Johnstone; Gian van der Spuy; Jeroen Maertzdorf; Stefan H E Kaufmann; Anneke C Hesseling; Gerhard Walzl; Mark F Cotton Journal: Clin Vaccine Immunol Date: 2017-02-06
Authors: H Simon Schaaf; Ben J Marais; Andrew Whitelaw; Anneke C Hesseling; Brian Eley; Gregory D Hussey; Peter R Donald Journal: BMC Infect Dis Date: 2007-11-29 Impact factor: 3.090