Literature DB >> 16825067

Recurrence of endometriomas after laparoscopic removal: sonographic and clinical follow-up and indication for second surgery.

Caterina Exacoustos1, Errico Zupi, Annalisa Amadio, Concetta Amoroso, Beata Szabolcs, Maria Elisabetta Romanini, Domenico Arduini.   

Abstract

STUDY
OBJECTIVE: This study involved patients who, after laparoscopic surgery, had recurrence of endometriomas detected by sonography. The aim of this study was to evaluate the role of transvaginal sonography (TVS) in the management of recurrent endometriomas and to establish ultrasonographic criteria that would direct the therapy toward additional surgery versus medical or expectant management.
DESIGN: Retrospective analysis of 62 reproductive-age women who showed recurrence of endometriomas on TVS after laparoscopic removal of an ovarian endometrioma by the stripping technique (Canadian Task Force classification II-1).
SETTING: Obstetrics and Gynecology Department, University of Rome Tor Vergata. PATIENTS: Sixty-two patients with recurrent endometriomas after first-line treatment with laparoscopy.
INTERVENTIONS: Ultrasonographic follow-up and/or second surgery.
MEASUREMENTS AND MAIN RESULTS: Recurrence of an ovarian endometrioma was defined as the presence of ovarian cysts with the typical sonographic criteria of endometriomas and a diameter of more than 10 mm. The clinical and sonographic postoperative follow-up period lasted from 6 to 97 months (median 24.6) after the first procedure. Of 62 patients with recurrent endometriomas, 50 had recurrence on the treated ovary, 7 on the contralateral untreated ovary, and 5 on both the treated and untreated ovaries. Recurrence of endometriomas was associated with symptoms (pain or infertility) in 47 patients (76%), while the remaining 15 (24%) were asymptomatic. Of the 47 symptomatic patients with recurrence detected by TVS, a second procedure was performed in 15. Second surgery in these patients was indicated by the larger size of the recurrent cysts, a poor response to medical treatment, the presence on TVS of pelvic adhesions and nodules of deep endometriosis, and overall progression of the disease. Symptomatic patients who did not undergo a second procedure (32) had smaller recurrent endometriomas. However of the 31 symptomatic patients with large recurrent endometriomas (>3 cm), only 45% had repeat surgery.
CONCLUSION: Recurrent endometriomas, as detected by TVS, can remain asymptomatic and do not necessarily progress in size with or without medical treatment. The decision to reoperate depends less on the endometrioma's size than on symptoms, in particular severe pain, and failure of medical treatment. However such patients are also more likely to have signs of deep nodules and adnexal/bowel adhesions and larger endometriomas on TVS scan, thus predisposing them to require a second procedure.

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Year:  2006        PMID: 16825067     DOI: 10.1016/j.jmig.2006.03.002

Source DB:  PubMed          Journal:  J Minim Invasive Gynecol        ISSN: 1553-4650            Impact factor:   4.137


  7 in total

1.  Risk factors for recurrence of ovarian endometriomas after surgical excision.

Authors:  Ming Yuan; Wen-Wen Wang; Yan Li; Ling Gao; Tian Wang; Shi-Xuan Wang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2014-04-08

2.  Influence of ovarian endometrioma on expression of steroid receptor RNA activator, estrogen receptors, vascular endothelial growth factor, and thrombospondin 1 in the surrounding ovarian tissues.

Authors:  Kaiqing Lin; Junyan Ma; Ruijin Wu; Caiyun Zhou; Jun Lin
Journal:  Reprod Sci       Date:  2013-06-07       Impact factor: 3.060

3.  Increased immunoreactivity to SLIT/ROBO1 in ovarian endometriomas: a likely constituent biomarker for recurrence.

Authors:  Fanghua Shen; Xishi Liu; Jian-Guo Geng; Sun-Wei Guo
Journal:  Am J Pathol       Date:  2009-07-16       Impact factor: 4.307

Review 4.  Endometriosis and tissue factor.

Authors:  Graciela Krikun; Frederick Schatz; Hugh Taylor; Charles J Lockwood
Journal:  Ann N Y Acad Sci       Date:  2008-04       Impact factor: 5.691

Review 5.  Recurrence of endometriosis; risk factors, mechanisms and biomarkers; review of the literature.

Authors:  Ilker Selçuk; Gürkan Bozdağ
Journal:  J Turk Ger Gynecol Assoc       Date:  2013-06-01

6.  Medical management of recurrent endometrioma with long-term norethindrone acetate.

Authors:  Ozgul Muneyyirci-Delale; Jenny Anopa; Cassandra Charles; Deepali Mathur; Rudolph Parris; Jed B Cutler; Ghadir Salame; Ovadia Abulafia
Journal:  Int J Womens Health       Date:  2012-03-30

Review 7.  An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women.

Authors:  Sanaz Keyhan; Claude Hughes; Thomas Price; Suheil Muasher
Journal:  Biomed Res Int       Date:  2015-07-09       Impact factor: 3.411

  7 in total

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