Literature DB >> 1682498

Variation in T-lymphocyte activation and susceptibility to SIVPBj-14-induced acute death in macaques.

Y J Rosenberg1, B D White, S F Papermaster, P Zack, P B Jarling, G A Eddy, D S Burke, M G Lewis.   

Abstract

In contrast to pig-tailed and cynomolgus macaques, which die in 6-10 days following infection with the SIV-PBj-14 isolate, only about 50% of rhesus succumbed to rapid disease. Using a CD45RA MAb that delineates memory (CD45RAlo), naive (CD45RAmed) and "activated" (CD45RAhi) T-cell subsets, it was seen that PBMC from pig-tailed and cynomolgus monkeys, unlike rhesus, have reduced CD4/CD8 ratios and a skewing of T cells towards CD45RAhi expression. Such preactivation of CD4+ cells could lead to enhanced viral replication and early death.

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Year:  1991        PMID： 1682498

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  8 in total

Review 1.  Animal models for microbicide studies.

Authors:  Ronald S Veazey; Robin J Shattock; Per Johan Klasse; John P Moore
Journal:  Curr HIV Res       Date:  2012-01-01       Impact factor: 1.581

2.  Immunodeficiency in the absence of high viral load in pig-tailed macaques infected with Simian immunodeficiency virus SIVsun or SIVlhoest.

Authors:  Brigitte E Beer; Charles R Brown; Sonya Whitted; Simoy Goldstein; Robert Goeken; Ronald Plishka; Alicia Buckler-White; Vanessa M Hirsch
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

3.  Differential pathogenicity of SHIV infection in pig-tailed and rhesus macaques.

Authors:  Patricia Polacino; Kay Larsen; Lindsey Galmin; John Suschak; Zane Kraft; Leonidas Stamatatos; David Anderson; Susan W Barnett; Ranajit Pal; Kristen Bost; A H Bandivdekar; Christopher J Miller; Shiu-Lok Hu
Journal:  J Med Primatol       Date:  2008-12       Impact factor: 0.667

4.  Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection.

Authors:  N R Klatt; L D Harris; C L Vinton; H Sung; J A Briant; B Tabb; D Morcock; J W McGinty; J D Lifson; B A Lafont; M A Martin; A D Levine; J D Estes; J M Brenchley
Journal:  Mucosal Immunol       Date:  2010-03-31       Impact factor: 7.313

5.  Immune activation and viral burden in acute disease induced by simian immunodeficiency virus SIVsmmPBj14: correlation between in vitro and in vivo events.

Authors:  R Schwiebert; P N Fultz
Journal:  J Virol       Date:  1994-09       Impact factor: 5.103

6.  Activation/proliferation and apoptosis of bystander goat lymphocytes induced by a macrophage-tropic chimeric caprine arthritis encephalitis virus expressing SIV Nef.

Authors:  Baya Amel Bouzar; Angela Rea; Stephanie Hoc-Villet; Céline Garnier; François Guiguen; Yuhuai Jin; Opendra Narayan; Yahia Chebloune
Journal:  Virology       Date:  2007-04-17       Impact factor: 3.616

7.  Dynamics of viral replication in blood and lymphoid tissues during SIVmac251 infection of macaques.

Authors:  Abdelkrim Mannioui; Olivier Bourry; Pierre Sellier; Benoit Delache; Patricia Brochard; Thibault Andrieu; Bruno Vaslin; Ingrid Karlsson; Pierre Roques; Roger Le Grand
Journal:  Retrovirology       Date:  2009-11-23       Impact factor: 4.602

8.  Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus.

Authors:  On Ho; Kay Larsen; Patricia Polacino; Yun Li; David Anderson; Ruijiang Song; Ruth M Ruprecht; Shiu-Lok Hu
Journal:  Retrovirology       Date:  2009-07-14       Impact factor: 4.602
  8 in total

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