| Literature DB >> 16824498 |
Isabelle Gorenne1, Mary Kavurma, Stephen Scott, Martin Bennett.
Abstract
Markers of cell senescence have been identified in both the blood and vessel wall of patients with atherosclerosis. In particular, vascular smooth muscle cells (VSMCs) derived from human plaques show numerous features of senescence both in culture and in vivo. This review summarises the evidence for VSMC senescence in atherosclerosis, and outlines the mechanisms and triggers leading to their senescence.Entities:
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Year: 2006 PMID： 16824498 DOI： 10.1016/j.cardiores.2006.06.004
Source DB: PubMed Journal: Cardiovasc Res ISSN： 0008-6363 Impact factor: 10.787