Literature DB >> 16824476

[Anaplastic thyroid carcinoma: aggressive radical resection and cervical reconstruction. A case report].

A-C Collin1, K Chekaroua, T Delaporte, J-P Droz, J-L Peix, E Delay.   

Abstract

STUDY AIM: Anaplastic carcinoma of the thyroid is a rare but highly malignant tumor. The goal of this study was to present the case of a patient who underwent a multimodal treatment and to analyze prognosis factors. PATIENT AND METHODS: We present the case of a patient treated in 1996 for an anaplasic thyroid carcinoma with cervical cutaneous invasion. The initial surgical procedure was a total thyroidectomy extended to the anterior cervical skin associated to bilateral neck dissection. The patient underwent a differed reconstruction with musculocutaneous latissimus dorsi flap. Management was then supplemented by radiotherapy and chemotherapy.
RESULTS: This patient is free of tumor 9 years after this multimodal management. She does not present any functionary sequela and plastic results of the reconstruction is considered as very satisfactory.
CONCLUSION: Anaplastic carcinoma is one of more aggressive neoplasm affecting humans. This case report suggests that multimodality therapy, including surgery, chemotherapy and radiotherapy may offer hope for long-term survival. A musculocutaneous latissimus dorsi flap is a reliable solution to cover this large cervical defect.

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Year:  2006        PMID: 16824476     DOI: 10.1016/j.anchir.2006.05.007

Source DB:  PubMed          Journal:  Ann Chir        ISSN: 0003-3944


  2 in total

1.  Association of TERT promoter mutation 1,295,228 C>T with BRAF V600E mutation, older patient age, and distant metastasis in anaplastic thyroid cancer.

Authors:  Xiaoguang Shi; Rengyun Liu; Shen Qu; Guangwu Zhu; Justin Bishop; Xiaoli Liu; Hui Sun; Zhongyan Shan; Enhua Wang; Yahong Luo; Xianghong Yang; Jiajun Zhao; Jianling Du; Adel K El-Naggar; Weiping Teng; Mingzhao Xing
Journal:  J Clin Endocrinol Metab       Date:  2015-01-13       Impact factor: 5.958

2.  A large nonmetastatic anaplastic thyroid cancer with complete thyroidal confinement.

Authors:  Jeffrey C Xing; Justin A Bishop; Nestoras Mathioudakis; Nishant Agrawal; Ralph P Tufano
Journal:  Case Rep Med       Date:  2011-09-07
  2 in total

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