BACKGROUND: Synthetic, osteoconductive, and antimicrobial bioactive glass (BAG) has been used in many surgical applications. METHODS: BAG was used as obliteration material in a series of osteoplastic frontal sinus operations on 42 patients suffering from chronic frontal sinusitis, which could not be cured with other means of treatment. RESULTS: Accurate obliteration of sinuses was achieved in 39 patients. Uneventful recovery and clinical outcome were seen in 92% of the patients. Histopathologic samples harvested at 1, 5, and 10 years after obliteration revealed a healing process progressing from the fibrous tissue phase to bone formation with scattered fibrous tissue and bony obliteration maintaining BAG granule remnants. Fourier-transform infrared (FTIR) studies showed bone produced by BAG to be similar to natural frontal bone. Micorobiologic cultures obtained with histologic samples revealed no growth of bacteria. CONCLUSIONS: BAG appears to be a reliable frontal sinus obliteration material, providing favorable conditions for total bony sinus obliteration. (c) 2006 Wiley Periodicals, Inc.
BACKGROUND: Synthetic, osteoconductive, and antimicrobial bioactive glass (BAG) has been used in many surgical applications. METHODS: BAG was used as obliteration material in a series of osteoplastic frontal sinus operations on 42 patients suffering from chronic frontal sinusitis, which could not be cured with other means of treatment. RESULTS: Accurate obliteration of sinuses was achieved in 39 patients. Uneventful recovery and clinical outcome were seen in 92% of the patients. Histopathologic samples harvested at 1, 5, and 10 years after obliteration revealed a healing process progressing from the fibrous tissue phase to bone formation with scattered fibrous tissue and bony obliteration maintaining BAG granule remnants. Fourier-transform infrared (FTIR) studies showed bone produced by BAG to be similar to natural frontal bone. Micorobiologic cultures obtained with histologic samples revealed no growth of bacteria. CONCLUSIONS: BAG appears to be a reliable frontal sinus obliteration material, providing favorable conditions for total bony sinus obliteration. (c) 2006 Wiley Periodicals, Inc.
Authors: R Pérez-Tanoira; M García-Pedrazuela; T Hyyrynen; A Soininen; A Aarnisalo; Mikko T Nieminen; V-M Tiainen; Y T Konttinen; T J Kinnari Journal: J Mater Sci Mater Med Date: 2015-09-24 Impact factor: 3.896
Authors: R Pérez-Tanoira; T J Kinnari; T Hyyrynen; A Soininen; L Pietola; V-M Tiainen; Y T Konttinen; A A Aarnisalo Journal: J Mater Sci Mater Med Date: 2015-09-28 Impact factor: 3.896
Authors: Matti J Peltola; Pekka K Vallittu; Ville Vuorinen; Allan A J Aho; Antti Puntala; Kalle M J Aitasalo Journal: Eur Arch Otorhinolaryngol Date: 2011-06-01 Impact factor: 2.503