Literature DB >> 16822224

Extended-release opioids for the management of chronic non-malignant pain.

Paul Sloan1, Najib Babul.   

Abstract

Recent clinical trials have documented the use of extended-release (ER) opioids in the management of chronic non-malignant pain. This manuscript reviews the clinical pharmacology of investigational and current marketed ER opioids. Recent randomised clinical trials of ER opioids that document the efficacy and safety of opioid therapy for chronic pain are reviewed. Finally, the abuse liability of ER opioids is discussed. Current technologies aimed at defeating the abuse of ER opioids will also be presented.

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Year:  2006        PMID： 16822224     DOI： 10.1517/17425247.3.4.489

Source DB:  PubMed          Journal:  Expert Opin Drug Deliv        ISSN： 1742-5247            Impact factor:   6.648


  7 in total

Review 1.  The Clinical Applications of Extended-Release Abuse-Deterrent Opioids.

Authors:  Nalini Vadivelu; Erika Schermer; Gopal Kodumudi; Jack M Berger
Journal:  CNS Drugs       Date:  2016-07       Impact factor: 5.749

2.  Formulation optimization of hot-melt extruded abuse deterrent pellet dosage form utilizing design of experiments.

Authors:  Sindhuri Maddineni; Sunil Kumar Battu; Joe Morott; Majumdar Soumyajit; Michael A Repka
Journal:  J Pharm Pharmacol       Date:  2013-08-20       Impact factor: 3.765

3.  Impact of intravenous naltrexone on intravenous morphine-induced high, drug liking, and euphoric effects in experienced, nondependent male opioid users.

Authors:  Lynn R Webster; Franklin K Johnson; Joseph Stauffer; Beatrice Setnik; Sabrina Ciric
Journal:  Drugs R D       Date:  2011-09-01

Review 4.  Impact of opioid rescue medication for breakthrough pain on the efficacy and tolerability of long-acting opioids in patients with chronic non-malignant pain.

Authors:  J Devulder; A Jacobs; U Richarz; H Wiggett
Journal:  Br J Anaesth       Date:  2009-09-06       Impact factor: 9.166

5.  Controlled release formulation of oxycodone in patients with moderate to severe chronic osteoarthritis: a critical review of the literature.

Authors:  Robert Taylor; Robert B Raffa; Joseph V Pergolizzi
Journal:  J Pain Res       Date:  2012-04-23       Impact factor: 3.133

6.  Review of oral oxymorphone in the management of pain.

Authors:  Paul Sloan
Journal:  Ther Clin Risk Manag       Date:  2008-08       Impact factor: 2.423

7.  Single-dose pharmacokinetics of 2 or 3 tablets of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) under fed and fasted conditions: two randomized open-label trials.

Authors:  Krishna Devarakonda; Kenneth Kostenbader; Michael J Giuliani; Jim L Young
Journal:  BMC Pharmacol Toxicol       Date:  2015-11-27       Impact factor: 2.483
  7 in total

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