Literature DB >> 16822074

Birefringence-based eye fixation monitor with no moving parts.

B I Gramatikov1, O H Y Zalloum, Y K Wu, D G Hunter, D L Guyton.   

Abstract

For the purpose of vision screening, we develop an eye fixation monitor that detects the fovea by its unique radial orientation of birefringent Henle fibers. Polarized near-infrared light is reflected from the foveal area in a bow-tie pattern of polarization states, similar to the Haidinger brush phenomenon. In contrast to previous devices that used scanning systems, this instrument uses no moving parts. It rather utilizes four spots of linearly polarized light-two aligned with the "bright" arms and two aligned with the "dark" arms-of the bow-tie pattern surrounding the fovea. The light reflected from the fundus is imaged onto a quadrant photodetector, whereby the circular polarization component of the polarization state of each reflected patch of light is measured. The signals from the four photodetectors are amplified, digitized, and analyzed. A normalized differential signal is computed to detect central fixation. The algorithm is tested on a computer model, and the apparatus is tested on human subjects. This work demonstrates the feasibility of a fixation monitor with no moving parts.

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Year:  2006        PMID: 16822074     DOI: 10.1117/1.2209003

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  9 in total

1.  Pupil tracking optical coherence tomography for precise control of pupil entry position.

Authors:  Oscar Carrasco-Zevallos; Derek Nankivil; Brenton Keller; Christian Viehland; Brandon J Lujan; Joseph A Izatt
Journal:  Biomed Opt Express       Date:  2015-08-17       Impact factor: 3.732

2.  Classification and misclassification of sensory monofixation in intermittent exotropia.

Authors:  Sarah R Hatt; David A Leske; Brian G Mohney; Michael C Brodsky; Jonathan M Holmes
Journal:  Am J Ophthalmol       Date:  2010-04-08       Impact factor: 5.258

3.  Foveal phase retardation changes associated with normal aging.

Authors:  Dean A VanNasdale; Ann E Elsner; Timothy Hobbs; Stephen A Burns
Journal:  Vision Res       Date:  2011-08-27       Impact factor: 1.886

4.  Determination of foveal location using scanning laser polarimetry.

Authors:  Dean A VanNasdale; Ann E Elsner; Anke Weber; Masahiro Miura; Bryan P Haggerty
Journal:  J Vis       Date:  2009-03-25       Impact factor: 2.240

5.  Modeling and minimizing interference from corneal birefringence in retinal birefringence scanning for foveal fixation detection.

Authors:  Kristina Irsch; Boris Gramatikov; Yi-Kai Wu; David Guyton
Journal:  Biomed Opt Express       Date:  2011-06-17       Impact factor: 3.732

6.  Detecting central fixation by means of artificial neural networks in a pediatric vision screener using retinal birefringence scanning.

Authors:  Boris I Gramatikov
Journal:  Biomed Eng Online       Date:  2017-04-27       Impact factor: 2.819

7.  Foveal Phase Retardation Correlates With Optically Measured Henle Fiber Layer Thickness.

Authors:  Phillip T Yuhas; Marisa L Ciamacca; Keith A Ramsey; Danielle M Mayne; Elizabeth A Stern-Green; Matthew Ohr; Aaron Zimmerman; Andrew T E Hartwick; Dean A VanNasdale
Journal:  Front Med (Lausanne)       Date:  2022-04-15

Review 8.  Modern technologies for retinal scanning and imaging: an introduction for the biomedical engineer.

Authors:  Boris I Gramatikov
Journal:  Biomed Eng Online       Date:  2014-04-29       Impact factor: 2.819

9.  New pediatric vision screener, part II: electronics, software, signal processing and validation.

Authors:  Boris I Gramatikov; Kristina Irsch; Yi-Kai Wu; David L Guyton
Journal:  Biomed Eng Online       Date:  2016-02-04       Impact factor: 2.819

  9 in total

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