Literature DB >> 16822033

Noise in genetic and neural networks.

Peter S Swain1, André Longtin.   

Abstract

Both neural and genetic networks are significantly noisy, and stochastic effects in both cases ultimately arise from molecular events. Nevertheless, a gulf exists between the two fields, with researchers in one often being unaware of similar work in the other. In this Special Issue, we focus on bridging this gap and present a collection of papers from both fields together. For each field, the networks studied range from just a single gene or neuron to endogenous networks. In this introductory article, we describe the sources of noise in both genetic and neural systems. We discuss the modeling techniques in each area and point out similarities. We hope that, by reading both sets of papers, ideas developed in one field will give insight to scientists from the other and that a common language and methodology will develop.

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Year:  2006        PMID: 16822033     DOI: 10.1063/1.2213613

Source DB:  PubMed          Journal:  Chaos        ISSN: 1054-1500            Impact factor:   3.642


  9 in total

1.  A microfluidic processor for gene expression profiling of single human embryonic stem cells.

Authors:  Jiang F Zhong; Yan Chen; Joshua S Marcus; Axel Scherer; Stephen R Quake; Clive R Taylor; Leslie P Weiner
Journal:  Lab Chip       Date:  2007-11-02       Impact factor: 6.799

2.  Fluctuations, pauses, and backtracking in DNA transcription.

Authors:  Margaritis Voliotis; Netta Cohen; Carmen Molina-París; Tanniemola B Liverpool
Journal:  Biophys J       Date:  2007-08-24       Impact factor: 4.033

Review 3.  From the stochasticity of molecular processes to the variability of synaptic transmission.

Authors:  Claire Ribrault; Ken Sekimoto; Antoine Triller
Journal:  Nat Rev Neurosci       Date:  2011-06-20       Impact factor: 34.870

4.  Tuning response curves for synthetic biology.

Authors:  Jordan Ang; Edouard Harris; Brendan J Hussey; Richard Kil; David R McMillen
Journal:  ACS Synth Biol       Date:  2013-09-03       Impact factor: 5.110

Review 5.  Quantification of variability in trichome patterns.

Authors:  Bettina Greese; Martin Hülskamp; Christian Fleck
Journal:  Front Plant Sci       Date:  2014-11-13       Impact factor: 5.753

6.  Investigating the impact of electrical stimulation temporal distribution on cortical network responses.

Authors:  Francesca Scarsi; Jacopo Tessadori; Michela Chiappalone; Valentina Pasquale
Journal:  BMC Neurosci       Date:  2017-06-12       Impact factor: 3.288

7.  A circadian clock-regulated toggle switch explains AtGRP7 and AtGRP8 oscillations in Arabidopsis thaliana.

Authors:  Christoph Schmal; Peter Reimann; Dorothee Staiger
Journal:  PLoS Comput Biol       Date:  2013-03-28       Impact factor: 4.475

8.  Increasing the efficiency of bacterial transcription simulations: when to exclude the genome without loss of accuracy.

Authors:  Marco A J Iafolla; Guang Qiang Dong; David R McMillen
Journal:  BMC Bioinformatics       Date:  2008-09-12       Impact factor: 3.169

9.  Recognizing student misconceptions through Ed's Tools and the Biology Concept Inventory.

Authors:  Michael W Klymkowsky; Kathy Garvin-Doxas
Journal:  PLoS Biol       Date:  2008-01       Impact factor: 8.029

  9 in total

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