Literature DB >> 16821707

New antimycobacterial 2,3-dihydro-1-alkylindole-2-thiones.

K Waisser1, L Heinisch, M Slosárek, J Janota.   

Abstract

A series of 2,3-dihydroindole-2-thiones was evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M. fortuitum, two strains of M. intracellulare and three strains of M. avium. 2,3-Dihydro-1-methyl-2-thioxoindole-3-one and 2,3-dihydro-1-butyl-2-thioxoindole-3-one were the most active substances against potentially pathogenic strains, being more active than isoniazide.

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Year:  2006        PMID： 16821707     DOI： 10.1007/BF02931445

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.629


  7 in total

1.  1-Aryl-5-benzylsulfanyltetrazoles, a new group of antimycobacterial compounds against potentially pathogenic strains.

Authors:  K Waisser; J Adamec; R Dolezal; J Kaustová
Journal:  Folia Microbiol (Praha)       Date:  2005       Impact factor: 2.099

2.  Influence of the replacement of the oxo function with the thioxo group on the antimycobacterial activity of 3-aryl-6,8-dichloro-2H-1,3-benzoxazine-2,4(3H)-diones and 3-arylquinazoline-2,4(1H,3H)-diones.

Authors:  K Waisser; J Gregor; H Dostál; J Kunes; L Kubicová; V Klimesová; J Kaustová
Journal:  Farmaco       Date:  2001-10

3.  [Advances in the development of new antitubercular agents from a group of 5-membered heterocyclic compounds containing one type of heteroatom].

Authors:  K Waisser; L Drhová
Journal:  Ceska Slov Farm       Date:  1999-07

4.  A new group of potential antituberculotics: hydrochlorides of piperidinylalkyl esters of alkoxy-substituted phenylcarbamic acids.

Authors:  K Waisser; K Drazková; J Cizmárik; J Kaustová
Journal:  Folia Microbiol (Praha)       Date:  2004       Impact factor: 2.099

5.  Antimycobacterial activity of piperidinylpropyl esters of alkoxy-substituted phenylcarbamic acids.

Authors:  K Waisser; K Drazková; J Cizmárik; J Kaustová
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.099

6.  New antimycobacterial S-alkylisothiosemicarbazones.

Authors:  K Waisser; L Heinisch; M Slosárek; J Janota
Journal:  Folia Microbiol (Praha)       Date:  2005       Impact factor: 2.629

7.  Antimycobacterial activity of basic ethyl esters of alkoxy-substituted phenylcarbamic acids.

Authors:  K Waisser; K Drazková; J Cizmárik; J Kaustová
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.629
  7 in total
  2 in total

1.  Azinyl sulfides--CXVIII. Antimicrobial activity of novel 1-methyl-3-thio-4-aminoquinolinium salts.

Authors:  A Zieba; R D Wojtyczka; M Kepa; D Idzik
Journal:  Folia Microbiol (Praha)       Date:  2010-03-25       Impact factor: 2.099

2.  Antimicrobial activity of a series of thiosemicarbazones and their Zn(II) and Pd(II) complexes.

Authors:  I Kizilcikli; Y D Kurt; B Akkurt; A Y Genel; S Birteksöz; G Otük; B Ulküseven
Journal:  Folia Microbiol (Praha)       Date:  2007       Impact factor: 2.629
  2 in total

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