| Literature DB >> 16821276 |
Ismail Sari1, Servet Akar, Merih Birlik, Banu Sis, Fatos Onen, Nurullah Akkoc.
Abstract
We describe a patient with rheumatoid arthritis who developed psoriasis during treatment with etanercept; psoriatic lesions resolved completely after the drug was discontinued, but returned on rechallenge. No such adverse skin reaction occurred after switching therapy to infliximab. Through a Medline search we identified 11 reports involving 32 patients who developed psoriasis/psoriasiform eruptions during therapy with tumor necrosis factor-alpha (TNF-alpha) inhibitors. All TNF-alpha blocking agents have been reported to lead to or exacerbate psoriasis. In some cases skin changes were severe enough to discontinue the medication.Entities:
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Year: 2006 PMID: 16821276
Source DB: PubMed Journal: J Rheumatol ISSN: 0315-162X Impact factor: 4.666