Literature DB >> 16819361

Heterotopic ossification revisited: a 21-year surgical experience.

John L Hunt1, Brett D Arnoldo, Karen Kowalske, Phala Helm, Gary F Purdue.   

Abstract

Heterotopic ossification (HO) is an infrequently encountered complication of a burn. A retrospective review was undertaken to evaluate our treatment and results. Forty-two patients were identified with HO during 21 yrs. Mean age was 38 yrs. Mean total body surface area and third-degree burn were 55% and 37%, respectively. The elbow was the most frequent site (>90%), and 44% were bilateral. The next most common sites were shoulder, hip, knee, and forearm. Greater than 90% of patients had ventilator support and intensive care unit length of stay 58 and 79 days, respectively. HO was first suspected by decreased range of motion, painful and/or swollen joint, or a nerve deficit. Conventional radiographs were used to confirm the clinical diagnosis. The majority of burns overlying joints with HO were associated with prolonged wound closure because of depth, wound infection, or graft loss. Mean day of diagnosis was 71 days (range, 21-134). Excision of HO was undertaken only when range of motion compromised activities of daily living. Surgery successfully improved range of motion in all cases. The mean elbow arc of motion before and after surgery was 52 degrees and 119 degrees (range, 30-180 degrees), respectively. Seventy percent of elbows were ankylosed. A continuous passive motion device was instituted immediately postoperatively. Local postoperative complications included hematoma, wound dehiscence, infection, and nerve deficit. Maintaining range of motion was difficult for 75% of patients. Symptomatic recurrence of HO occurred in four elbows and one forearm. Because the cause(s) are unknown, prevention is impossible; once diagnosed, medical treatment is problematic and spontaneous resolution is infrequent. Surgery continues to be the recommended treatment when activities of daily living or life style are affected.

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Year:  2006        PMID: 16819361     DOI: 10.1097/01.BCR.0000226023.58438.14

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  19 in total

1.  Direct Mouse Trauma/Burn Model of Heterotopic Ossification.

Authors:  Jonathan R Peterson; Shailesh Agarwal; R Cameron Brownley; Shawn J Loder; Kavitha Ranganathan; Paul S Cederna; Yuji Mishina; Stewart C Wang; Benjamin Levi
Journal:  J Vis Exp       Date:  2015-08-06       Impact factor: 1.355

2.  Heterotopic ossification of the elbows in a major petrol burn.

Authors:  Shahriar Raj Zaman
Journal:  BMJ Case Rep       Date:  2012-08-27

3.  Treatment of heterotopic ossification through remote ATP hydrolysis.

Authors:  Jonathan R Peterson; Sara De La Rosa; Oluwatobi Eboda; Katherine E Cilwa; Shailesh Agarwal; Steven R Buchman; Paul S Cederna; Chuanwu Xi; Michael D Morris; David N Herndon; Wenzhong Xiao; Ronald G Tompkins; Paul H Krebsbach; Stewart C Wang; Benjamin Levi
Journal:  Sci Transl Med       Date:  2014-09-24       Impact factor: 17.956

4.  Treatment and Rehabilitation of Knee Joints Straight Stiffness After Burns.

Authors:  Jinshu Tang; Minghuo Xu; Wenwen Wu; Yuan Hu; Xiuxiu Shi; Shuxun Hou
Journal:  Indian J Surg       Date:  2014-09-24       Impact factor: 0.656

5.  Heterotopic ossification of the elbow treated with surgical resection: risk factors, bony ankylosis, and complications.

Authors:  Dane Salazar; Andrew Golz; Heidi Israel; Guido Marra
Journal:  Clin Orthop Relat Res       Date:  2014-04-08       Impact factor: 4.176

6.  Risk factors for the development of heterotopic ossification in seriously burned adults: A National Institute on Disability, Independent Living and Rehabilitation Research burn model system database analysis.

Authors:  Benjamin Levi; Prakash Jayakumar; Avi Giladi; Jesse B Jupiter; David C Ring; Karen Kowalske; Nicole S Gibran; David Herndon; Jeffrey C Schneider; Colleen M Ryan
Journal:  J Trauma Acute Care Surg       Date:  2015-11       Impact factor: 3.313

7.  Early detection of burn induced heterotopic ossification using transcutaneous Raman spectroscopy.

Authors:  Jonathan R Peterson; Paul I Okagbare; Sara De La Rosa; Katherine E Cilwa; Joseph E Perosky; Oluwatobi N Eboda; Alexis Donneys; Grace L Su; Steven R Buchman; Paul S Cederna; Stewart C Wang; Kenneth M Kozloff; Michael D Morris; Benjamin Levi
Journal:  Bone       Date:  2013-01-11       Impact factor: 4.398

Review 8.  Peripheral Neuropathy and Nerve Compression Syndromes in Burns.

Authors:  Amy L Strong; Shailesh Agarwal; Paul S Cederna; Benjamin Levi
Journal:  Clin Plast Surg       Date:  2017-07-21       Impact factor: 2.017

9.  High-frequency spectral ultrasound imaging (SUSI) visualizes early post-traumatic heterotopic ossification (HO) in a mouse model.

Authors:  Kavitha Ranganathan; Xiaowei Hong; David Cholok; Joe Habbouche; Caitlin Priest; Christopher Breuler; Michael Chung; John Li; Arminder Kaura; Hsiao Hsin Sung Hsieh; Jonathan Butts; Serra Ucer; Ean Schwartz; Steven R Buchman; Jan P Stegemann; Cheri X Deng; Benjamin Levi
Journal:  Bone       Date:  2018-02-14       Impact factor: 4.398

10.  Predicting Heterotopic Ossification Early After Burn Injuries: A Risk Scoring System.

Authors:  Jeffrey C Schneider; Laura C Simko; Richard Goldstein; Vivian L Shie; Betty Chernack; Benjamin Levi; Prakash Jayakumar; Karen J Kowalske; David N Herndon; Nicole S Gibran; Colleen M Ryan
Journal:  Ann Surg       Date:  2017-07       Impact factor: 13.787

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