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Literature DB >> 16819346

Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury.

Matthew B Klein¹, Geoff Silver, Richard L Gamelli, Nicole S Gibran, David N Herndon, John L Hunt, Ronald G Tompkins.

Abstract

Inflammation and the Host Response to Injury is a prospective, multicenter, federally funded collaborative study of the genomic and proteomic basis for injury response. This study has brought together clinical specialists in burn injury with experts in genomics, proteomics, and bioinformatics to answer questions related to immunoinflammatory responses to injury. The purpose of this report is to describe the structure, organization, goals, and current progress of this Glue Grant project.

Entities: Disease

Mesh：

Year: 2006 PMID： 16819346 DOI： 10.1097/01.BCR.0000227477.33877.E6

Source DB: PubMed Journal: J Burn Care Res ISSN： 1559-047X Impact factor: 1.845

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Cited

23 in total

1. Coding SNPs as intrinsic markers for sample tracking in large-scale transcriptome studies.

Authors: Weihong Xu; Hong Gao; Junhee Seok; Julie Wilhelmy; Michael N Mindrinos; Ronald W Davis; Wenzhong Xiao
Journal: Biotechniques Date: 2012-06 Impact factor: 1.993

Review 2. Translational potential of systems-based models of inflammation.

Authors: P T Foteinou; S E Calvano; S F Lowry; I P Androulakis
Journal: Clin Transl Sci Date: 2009-02 Impact factor: 4.689

3. Early leukocyte gene expression associated with age, burn size, and inhalation injury in severely burned adults.

Authors: Ravi F Sood; Nicole S Gibran; Brett D Arnoldo; Richard L Gamelli; David N Herndon; Ronald G Tompkins
Journal: J Trauma Acute Care Surg Date: 2016-02 Impact factor: 3.313

Review 4. The Burn Wound Microenvironment.

Authors: Lloyd F Rose; Rodney K Chan
Journal: Adv Wound Care (New Rochelle) Date: 2016-03-01 Impact factor: 4.730

5. Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response.

Authors: Marc G Jeschke; Celeste C Finnerty; David N Herndon; Juquan Song; Darren Boehning; Ronald G Tompkins; Henry V Baker; Gerd G Gauglitz
Journal: Ann Surg Date: 2012-02 Impact factor: 12.969

Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury.

1. Coding SNPs as intrinsic markers for sample tracking in large-scale transcriptome studies.

Review 2. Translational potential of systems-based models of inflammation.

3. Early leukocyte gene expression associated with age, burn size, and inhalation injury in severely burned adults.

Review 4. The Burn Wound Microenvironment.

5. Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response.

Review 6. Specific Etiologies Associated With the Multiple Organ Dysfunction Syndrome in Children: Part 2.

7. Retinol binding protein: marker for insulin resistance and inflammation postburn?

8. Association of postburn fatty acids and triglycerides with clinical outcome in severely burned children.

9. Differences in resuscitation in morbidly obese burn patients may contribute to high mortality.

10. Renal dysfunction in burns: a review.