Literature DB >> 16816837

Current status and future prospects of needle-free liquid jet injectors.

Samir Mitragotri1.   

Abstract

Needle-free liquid jet injectors have been used for more than 50 years for parenteral delivery of vaccines and drugs. Although excellent bioavailability has been reported for a number of drugs, occasional pain and bruising have limited wide acceptance of jet injectors. This article reviews jet injectors with respect to their current clinical applications, emerging applications, mechanistic understanding and future prospects.

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Year:  2006        PMID: 16816837     DOI: 10.1038/nrd2076

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  47 in total

1.  Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets.

Authors:  Anubhav Arora; Itzhak Hakim; Joy Baxter; Ruben Rathnasingham; Ravi Srinivasan; Daniel A Fletcher; Samir Mitragotri
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-06       Impact factor: 11.205

Review 2.  Micro-scale devices for transdermal drug delivery.

Authors:  Anubhav Arora; Mark R Prausnitz; Samir Mitragotri
Journal:  Int J Pharm       Date:  2008-08-30       Impact factor: 5.875

Review 3.  Transdermal delivery of proteins.

Authors:  Haripriya Kalluri; Ajay K Banga
Journal:  AAPS PharmSciTech       Date:  2011-03-03       Impact factor: 3.246

4.  Numerical investigations on bubble-induced jetting and shock wave focusing: application on a needle-free injection.

Authors:  Nikolaos Kyriazis; Phoevos Koukouvinis; Manolis Gavaises
Journal:  Proc Math Phys Eng Sci       Date:  2019-02-20       Impact factor: 2.704

Review 5.  Non-invasive delivery strategies for biologics.

Authors:  Aaron C Anselmo; Yatin Gokarn; Samir Mitragotri
Journal:  Nat Rev Drug Discov       Date:  2018-11-30       Impact factor: 84.694

6.  Does needle size matter?

Authors:  Harvinder S Gill; Mark R Prausnitz
Journal:  J Diabetes Sci Technol       Date:  2007-09

7.  Diffusion behaviors of fluorescence probe molecules through the stratum corneum layer under physical stress.

Authors:  Ho Lee; Jin Woong Kim
Journal:  J Membr Biol       Date:  2013-01-31       Impact factor: 1.843

Review 8.  Microneedle arrays for the treatment of chronic wounds.

Authors:  Lindsay Barnum; Mohamadmahdi Samandari; Tannin A Schmidt; Ali Tamayol
Journal:  Expert Opin Drug Deliv       Date:  2020-10-08       Impact factor: 6.648

9.  Vector optimization and needle-free intradermal application of a broadly protective polyvalent influenza A DNA vaccine for pigs and humans.

Authors:  Marie Borggren; Jens Nielsen; Karoline Bragstad; Ingrid Karlsson; Jesper S Krog; James A Williams; Anders Fomsgaard
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

Review 10.  Cutaneous immunization: an evolving paradigm in influenza vaccines.

Authors:  Harvinder S Gill; Sang-Moo Kang; Fu-Shi Quan; Richard W Compans
Journal:  Expert Opin Drug Deliv       Date:  2014-02-12       Impact factor: 6.648

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